Results 131 to 140 of about 811,009 (286)

Non-parametric calibration estimation of distribution function under stratified random sampling

open access: yesAIMS Mathematics
We introduced an innovative kernel-based nonparametric estimator for the cumulative distribution function (CDF) in finite populations, addressing the critical need to evaluate the proportion of values in a target variable that are less than or equal to ...
Abdullah Mohammed Alomair   +3 more
doaj   +1 more source

Developing Improved Predictive Estimator for Finite Population Mean Using Auxiliary Information [PDF]

open access: yesStatistika: Statistics and Economy Journal, 2015
The present paper deals with the estimation of population mean using predictive method of estimation utilizing auxiliary information. In this paper, we have proposed improved ratio cum product type predictive estimators to estimate the population mean ...
Subhash Kumar Yadav, Sant Sharan Mishra
doaj  

Covariance matrix completion via auxiliary information

open access: yes
18 pages, 9 ...
Steneman, Joseph, Vinci, Giuseppe
openaire   +2 more sources

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Design of moving average chart and auxiliary information based chart using extended EWMA. [PDF]

open access: yesSci Rep, 2023
Naveed M   +5 more
europepmc   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

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