Results 61 to 70 of about 15,713,609 (295)
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Women's Auxiliary of the Children's Convalescent Center of Arkansas collection
, 1947 This collection contains correspondence, minutes, and a yearbook from the Women's Auxiliary of the Children's Convalescent Center of Arkansas, located in Jacksonville, covering the years 1947 ...
Children's Convalescent Center of Arkansas. Women's Auxiliary. (Jacksonville, Ark.)
core +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
, 1960 Members of the Ladies Auxiliary of the Long Beach Fire Department pose at unnamed ...
core +3 more sources
Dual Transformation of Auxiliary Variables by Using Outliers in Stratified Random Sampling
MathematicsTo estimate the finite population variance of the study variable, this paper proposes an improved class of efficient estimators using different transformations. When both the minimum and maximum values of the auxiliary variable are known and the ranks of
Mohammed Ahmed Alomair, Umer Daraz
doaj +1 more source
An Efficient Estimation Procedure for the Population Mean under Non-Response
Statistica, 2020 This paper introduces an efficient estimation procedure for the population mean in the presence of non-response. The proposed estimators of population mean provides an improvement over the corresponding conventional estimators proposed by Cochran (1977),
Shashi Bhushan, Abhay Pratap Pandey
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
, 1959 Group standing by Christmas stocking being presented by Auxiliary.Presentation of the Christmas stocking donated by the Lyell McEwin Hospital Auxiliary to the winner Mrs.
core +1 more source