Results 191 to 200 of about 278,622 (265)

High-dimensional multiple imputation for partially observed confounders including natural language processing-derived auxiliary covariates. [PDF]

Am J Epidemiol
Weberpals J, Shaw PA, Lin KJ, Wyss R, Plasek JM, Zhou L, Ngan K, DeRamus T, Raman SR, Hammill BG, Lee H, Toh S, Connolly JG, Dandreo KJ, Tian F, Liu W, Li J, Hernández-Muñoz JJ, Schneeweiss S, Desai RJ.   +19 more
europepmc   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Subciliary Closure in Orbital Fractures: A Comparison Between Cutaneous and Cutaneo-periosteal Sutures. [PDF]

Plast Reconstr Surg Glob Open
Castillo-Cardiel MG, Piña-Diaz DI, Ledezma-Rodríguez VC, Capetillo-Texson CE, García A, Monteon-Aspeitia X, Capetillo-Texson AP, Guzmán-Diaz JM, González-Ojeda A, Cervantes-Guevara G, Cervantes-Pérez E, Ramírez-Ochoa S, Álvarez-Villaseñor AS, Flores-Hernández D, Fuentes-Orozco C.   +14 more
europepmc   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

New data on long-jawed spiders (Araneae, Tetragnathidae, <i>Tetragnatha</i>) from China. [PDF]

Zookeys
Liu C, Huang Z, Yin H, Xu X.
europepmc   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Identification and validation of postpartum depression subtypes: a population-based cohort study. [PDF]

EClinicalMedicine
Bauer AE, Jaholkowski P, Lu Y, Guintivano J, Hannigan LJ, Corfield EC, Tesli M, Andreassen OA, Li Y, Reichborn-Kjennerud T, Sullivan PF, Meltzer-Brody S, Havdahl A, Ask H.   +13 more
europepmc   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Auxiliary diagnosis of hyperpigmented skin diseases using multimodal deep learning. [PDF]

Chin Med J (Engl)
Li T, Zhang J, Li B, Chen Y, Jia Y, Wang Q, Li X, Li H, Li Y, Yang X, Cai H.   +10 more
europepmc   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source