Study on the failure effect of gas tunnel blasting considering the influence of delay time and its engineering application. [PDF]
Sun Y +6 more
europepmc +1 more source
The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav +4 more
wiley +1 more source
Factors Associated with Uncomplicated Single-Session Stone-Free Status After Retrograde Intrarenal Surgery for Large Renal Stones. [PDF]
Kartal İ +7 more
europepmc +1 more source
MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima +8 more
wiley +1 more source
Beyond Bilateralism: Regional and Global Health Governance Implications of China-Pakistan Health Cooperation under the CPEC. [PDF]
Jian G, Ziheng X, Qiumei Q.
europepmc +1 more source
IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley +1 more source
Breast Cancer Awareness and Self-screening Behaviors among Female Nursing Trainees in Northern India. [PDF]
Singh S +4 more
europepmc +1 more source
Adaptation of Soil Viruses to Salinity Stress: Insights Into Genome Size Expansion and Functional Diversification. [PDF]
Kudureti A +4 more
europepmc +1 more source
Ten simple rules for making the supplement increase your paper's impact. [PDF]
Grimm V, Berger U, Mammola S.
europepmc +1 more source
Association of internet-integrated palliative care pathway assignment with recorded quality-of-life and symptom-burden scores in patients with terminal cancer: a single-center retrospective propensity score-matched cohort study. [PDF]
Xin J, Li N, Sun J, Wu X, Li C.
europepmc +1 more source

