Results 11 to 20 of about 540 (108)

Leveraging computer-aided drug design for the discovery of phytohormone analogs: A review

Plant Stress
Natural phytohormones regulate plant growth, development, and stress responses, but discovering novel analogs is challenging due to complex signaling pathways, limited structural diversity, and the high cost of conventional methods.
Yuling Guo, Ghulam Qanmber, Zhao Liu, Han Yang, Jun Li, Zhikun Yang, Zhongxian Li, Linlin Yang, Zuoren Yang   +8 more
doaj   +2 more sources

The optimization of crop response to climatic stress through modulation of plant stress response mechanisms. Opportunities for biostimulants and plant hormones to meet climate challenges. [PDF]

New Phytol
Summary This review discusses the use of agronomic management practices to enhance crop stress resilience to climate stress through the modulation of natural plant growth regulatory pathways. The use of biostimulants or plant hormones to improve crop resilience is subject to strict regulatory oversight if changes in the regulation of plant growth are ...
Li J, Forghieri G, Geelen D, du Jardin P, Brown PH.   +4 more
europepmc   +2 more sources

In vitro dynamic and quantitative monitoring of strigolactone-signaling complex formation by time-resolved FRET. [PDF]

Plant J
We developed a new in vitro method using time‐resolved FRET to evaluate the dynamic activation of the strigolactone (SL) receptors. This system was used to gain deeper insights into the molecular mechanism of SL‐signaling complex formation and to detect naturally occurring SLs.
Suzuki T, Nishiyama K, Kato Y, Shinkai C, Ishikawa T, Robertlee J, Kuruma M, Hagihara S, Bürger M, Fukui K, Asami T, Seto Y.   +11 more
europepmc   +2 more sources

A Reactive Antagonist Strategy: Cysteine-Directed Covalent Molecular Glue in Plant Hormone Receptor Regulation. [PDF]

Adv Sci (Weinh)
The plant hormone jasmonate is perceived by COI1‐JAZ co‐receptors comprising a single F‐box protein COI1 and multiple JAZ repressors with overlapping functions, complicating genetic analysis. We present a reactive antagonist (RA) strategy that selectively promotes COI1 binding to a cysteine‐engineered JAZ variant while blocking wild‐type JAZs, enabling
Ueda M, Matsumoto K, Nomura T, Takaoka Y, Okumura T, Kozaki W, Hoshikawa H, Nishizato Y, Chini A, Solano R, Maenaka K.   +10 more
europepmc   +2 more sources

Parasitic Plant-Host Interactions: Molecular Mechanisms and Agricultural Resistance Strategies. [PDF]

Adv Sci (Weinh)
Parasitic plants devastate global agriculture through sophisticated molecular interactions with host crops. This review synthesizes current understanding of parasitic plant‐host interactions, from strigolactone‐mediated germination and haustorium formation to host defense mechanisms.
Shi J, Xie Q, Yu F.
europepmc   +2 more sources

Ectopic sodium channel expression decreases excitability of Drosophila Kenyon cells. [PDF]

J Physiol
Abstract figure legend: We tested the effects of expressing the bacterial voltage‐gated sodium channel NaChBac in the Kenyon cells of the Drosophila memory centre, the mushroom body. NaChBac expression decreases expression of endogenous voltage‐gated sodium channels (left), reduces action potential firing (upper) and prevents learning (lower). However,
Greenin-Whitehead K, Rozenfeld E, Moreno-Sanchez A, Tan MW, Kullu K, Ausborn J, Parnas M, Lin AC.   +7 more
europepmc   +2 more sources

Advances and opportunities for computational interrogation of plant proteins. [PDF]

Plant J
SUMMARY Plants exhibit remarkable biochemical and physiological diversity, and are capable of adapting to a wide range of environmental conditions and stresses. This complexity makes them essential systems for understanding how life responds to a changing climate.
Bohling SM, Musharoff S, Gunn LH.
europepmc   +2 more sources

Data_Sheet_1_Design, Synthesis, and Action Mechanism of 1,3-Benzodioxole Derivatives as Potent Auxin Receptor Agonists and Root Growth Promoters.docx

, 2022
Deeper and longer roots allow crops to survive and flourish, but our understanding of the plant growth regulators promoting root system establishment is limited. Here, we report that, a novel auxin receptor agonist, named K-10, had a remarkable promotive
Lin Du (311554), Jiahui Xu (3156327), Fei Yi (351486), Kai Shu (424728), Zhaohu Li (146017), Weiming Tan (566475), Zhikun Yang (2235850), Jiaming Yin (12564307), Liusheng Duan (289755), Zhao Wang (145195), Baomin Wang (174006)   +10 more
core   +1 more source

A combinatorial TIR1/AFB–Aux/IAA co-receptor system for differential sensing of auxin [PDF]

, 2012
The plant hormone auxin regulates virtually every aspect of plant growth and development. Auxin acts by binding the F-box protein transport inhibitor response 1 (TIR1) and promotes the degradation of the AUXIN/INDOLE-3-ACETIC ACID (Aux/IAA ...
Calderón Villalobos, Luz Irina A, Zheng, Ning, Luz Irina A Calderón Villalobos, Parry, Geraint, Kepinski, Stefan, Estelle, Mark, Stefan Kepinski, Oliveira, Cesar de, Ning Zheng, Xu Tan, Sheard, Laura B., Luz Irina A. Calderón Villalobos, Wolfgang Brandt, Lynne Armitage, Napier, R. (Richard), Sarah Lee, Geraint Parry, Armitage, Lynne, Tan, Xu, Wolfgang Br, Brandt, Wolfgang, Laura B. Sheard, Haibin Mao, Mao, Haibin, Lee, Sarah C., Richard Napier, Laura B Sheard, Ivetac, Anthony, Cesar De Oliveira, Mark Estelle, Anthony Ivetac   +30 more
core   +1 more source

Defining binding efficiency and specificity of auxins for SCFTIR1/AFB-Aux/IAA co-receptor complex formation [PDF]

, 2014
Structure–activity profiles for the phytohormone auxin have been collected for over 70 years, and a number of synthetic auxins are used in agriculture. Auxin classification schemes and binding models followed from understanding auxin structures. However,
Evans, John P., Napier, R. (Richard), Ferro, N, Armitage, Lynne, Hawkes, Tim, Sundaram, S, Kepinski, S, Kepinski, Stefan, Lee, Sarah C., Hawkes, T, Armitage, L, Evans, JP, Sundaram, Shanthy, Napier, RM, Lee, S, Ferro, Noel   +15 more
core   +1 more source