Results 21 to 30 of about 267,234 (181)
During development, the oxygen‐sensitive transcription factor Zeb2 restrains astrocyte proliferation and maturation to ensure balanced retinal angiogenesis. In disease, it promotes the neurotoxic A1 astrocyte phenotype and inflammation, thereby promoting reparative revascularization over pathological neovascularization.
Jing Liu +5 more
wiley +1 more source
High‐Throughput Optimization of Organic Photovoltaics for Performance and Stability
HOOPS is an example navigation method for experiment design and decision making while optimizing OPV devices for both performance and stability at the earliest stages of device R&D, in order to rapidly transition from novel material choices to large‐area devices.
Rosemary M. Thompson +6 more
wiley +1 more source
Visual difficulty with internet‐enabled devices among older adults with low vision
ABSTRACT Purpose Vision rehabilitation practitioners provide support for visual difficulty with internet devices by prescribing optical aids and/or help with accessibility features (e.g., enlarged text or enhanced contrast), but it is unknown which patients continue to experience significant difficulty with various internet devices.
Alexis G. Malkin +10 more
wiley +1 more source
Analysing the influence of different elastic parameterizations in AVA-petrophysical inversion and in litho-fluid facies classification for a reservoir located in offshore Egypt [PDF]
I study the influence of different elastic parametrizations in amplitude versus angle (AVA)-petrophysical inversion and in litho-fluid facies identification with a focus on a reservoir located in offshore Egypt. Concerning the AVA-petrophysical inversion,
Mattia Aleardi
core +1 more source
Abstract Glacier bed topography is crucial for modeling ice mass loss. However, heavily crevassed regions are challenging to survey using conventional methods, leading to data gaps. We establish a passive seismic approach exploiting naturally occurring crevassing events recorded with a dense seismic array to image the ice–bed interface without spatial ...
Nicolas Paris +9 more
wiley +1 more source
Gonzalez Martinez and collaborators develop a strategy to formulate high performance GelMA‐based bioinks with low solids contents. The resulting bioinks enable 3D bioprinting at 37 °C of high‐fidelity structures with tunable mechanical properties that support high cell viability and function.
David A. González‐Martínez +8 more
wiley +1 more source
Compressed Multi-Trace Pre-Stack Inversion with Elastic Half-Norm Regularization
Multi-trace amplitude variation with angle inversion (MAVAI) is a vital tool for estimating the physical parameters of subsurface media, and it plays an important role in oil and gas exploration. However, the existing MAVAI method relies on the Kronecker
Nanying Lan +7 more
doaj +1 more source
A microfluidic device with magnetic microposts was used to assess platelet mechanobiology. The oscillatory actuation of posts with embedded iron particles was dampened by the dynamic stiffening of the platelet‐rich plugs. This stiffening process increased with applied load, but inhibiting platelet activation (ASA) or myosin contractility (blebbistatin)
Nikita Taparia +4 more
wiley +1 more source
Gellan gum fluid gel (FG) enables controlled ocular delivery of mesenchymal stromal cell (MSC)‐derived extracellular vesicles (EV). Its shear‐thinning, solid‐liquid‐solid rheology ensures prolonged ocular retention. Sustained MSC‐EV release (∼18% in 6 hrs) supports effective EV ocular delivery.
Seyedmohammad Moosavizadeh +7 more
wiley +1 more source
Delivery Systems for Therapeutic Genome Editing: Challenges, Innovations, and Future Perspectives
Schematic illustration of four emerging CRISPR–Cas delivery platforms defined by distinct design principles and structural features: virus‐mimicking nanosystems (e.g., VLPs), cell‐derived extracellular vesicles, cell‐penetrating peptides, and stimuli‐responsive scaffolds. These platforms enable spatiotemporally controlled delivery of RNPs, mRNA, or DNA
Meijia Yang +9 more
wiley +1 more source

