Results 11 to 20 of about 12,848,328 (154)

Distortion in the Communication of Nonsignificant Primary Outcomes: The Spin Strategy in Multiple Sclerosis Trials. [PDF]

Ann Neurol
Objective Spin refers to reporting strategies that highlight the benefits of an experimental treatment or divert attention from nonsignificant primary outcomes. We aimed to assess spin in randomized controlled trials (RCTs) on pharmaceutical efficacy in multiple sclerosis (MS) and explore associated factors.
Mascareñas-García M, Rivero-de-Aguilar A, Candal-Pedreira C, García G, Guerra-Tort C, Martín-Gisbert L, Rey-Brandariz J, Ríos MP, Casal-Acción B, Santiago-Pérez MI, Varela-Lema L.   +10 more
europepmc   +2 more sources

Motivations to donate blood and plasma: A scoping review of quantitative studies. [PDF]

Transfusion
Abstract Introduction Effective recruitment and retention of donors are essential for the supply of blood components and blood‐derived medicines. In many high‐income Western countries, there is an imbalance between demand and production of blood‐derived medicines.
Suárez-Artime P, Rey-Brandariz J, López García M, Casal Acción B, de Rivero de Aguilar Pensado A, Varela-Lema L.   +5 more
europepmc   +2 more sources

Sentinel Networks for the Surveillance of Overweight and Obesity: A Scoping Review. [PDF]

Obes Rev
ABSTRACT Introduction To address the high prevalence and significant burden of overweight and obesity, surveillance through sentinel networks should be considered. The aim of this review is to identify the sentinel surveillance networks in relation to overweight and obesity and to describe their characteristics and methodology. Methods A scoping review
García G, Candal-Pedreira C, Martin-Gisbert L, Teijeiro A, Rey-Brandariz J, Casal-Acción B, Varela-Lema L, Pérez-Ríos M.   +7 more
europepmc   +2 more sources

Burnout During Residency: A Thematic Analysis of Stressors, Coping, and Organisational Challenges Among Nursing Residents [PDF]

Global Qualitative Nursing Research
Burnout is a pervasive challenge among healthcare professionals in training, with significant implications for both well-being and quality of care. This qualitative study, using a phenomenological design, explored the experiences of nursing residents ...
Macarena Chacón-Docampo, Ángela Asensio-Martínez, David Liñares, Luis-Javier Márquez-Álvarez, Marina Feijoo Barbeito, Ana Clavería   +5 more
doaj   +2 more sources

Advancing digital health literacy in cancer care: Recommendations from two nominal group technique workshops in the TRANSiTION project [PDF]

Open Research Europe
Background Cancer is a major cause of mortality and morbidity in Europe, with increasing focus on integrating digital health tools to ensure safe, patient-centred, and equitable oncology care ...
David Liñares, Noemí López-Rey, Andreas Charalambous, Constantina Cloconi, Dimitrios Protogiros, Efthyvoulos Kyriacou, Iolie Nicolaidou, Nikolina Dodlek, Theologia Tsitsi, Álvaro Jimber, Norbert Couespel, Ana Clavería   +11 more
doaj   +4 more sources

Factors associated with burnout among Family and Community Medicine and Nursing residents: secondary analysis of a multicentre study [PDF]

BMC Nursing
Introduction Healthcare workers, especially medical and nursing residents, are exposed to situations that can lead to burnout. The main factors are organizational. However, it is more feasible for professionals to act on personal factors.
Macarena Chacón-Docampo, Ángela Asensio-Martínez, Sara Rodríguez-Pastoriza, David Liñares-Mariñas, María Victoria Martín-Miguel, Cruz Bartolomé-Moreno, Clara González-Formoso, Ana Clavería   +7 more
doaj   +2 more sources

The MegaPool Approach to Characterize Adaptive CD4+ and CD8+ T Cell Responses

Current Protocols, Volume 3, Issue 11, November 2023., 2023
Abstract Epitopes recognized by T cells are a collection of short peptide fragments derived from specific antigens or proteins. Immunological research to study T cell responses is hindered by the extreme degree of heterogeneity of epitope targets, which are usually derived from multiple antigens; within a given antigen, hundreds of different T cell ...
Ricardo da Silva Antunes, Daniela Weiskopf, John Sidney, Paul Rubiro, Bjoern Peters, Cecilia S. Lindestam Arlehamn, Alba Grifoni, Alessandro Sette   +7 more
wiley   +1 more source

Safety, pharmacokinetics and antiviral activity of ABI‐H2158, a hepatitis B virus core inhibitor: A randomized, placebo‐controlled phase 1 study

Journal of Viral Hepatitis, Volume 30, Issue 3, Page 209-222, March 2023., 2023
Abstract Treatment for chronic hepatitis B virus infection (cHBV) is mostly indefinite, with new finite‐duration therapies needed. We report safety, pharmacokinetics and antiviral activity of the investigational HBV core inhibitor ABI‐H2158. This Phase 1a/b study (NCT03714152) had three parts: Part A, participants received a single ascending oral dose ...
Kosh Agarwal, Jia Xu, Edward J. Gane, Tuan T. Nguyen, Yanhua Ding, Steven J. Knox, Katia Alves, Marc Evanchik, Katie Zomorodi, Julie Ma, Ran Yan, Qi Huang, Richard Colonno, Luisa M. Stamm, Tarek I. Hassanein, Dong Joon Kim, Young‐Suk Lim, Man‐Fung Yuen   +17 more
wiley   +1 more source

Detecting and reducing heterogeneity of error in acoustic classification

Methods in Ecology and Evolution, Volume 13, Issue 11, Page 2559-2571, November 2022., 2022
Abstract Passive acoustic monitoring can be an effective method for monitoring species, allowing the assembly of large audio datasets, removing logistical constraints in data collection and reducing anthropogenic monitoring disturbances. However, the analysis of large acoustic datasets is challenging and fully automated machine learning processes are ...
Oliver C. Metcalf, Jos Barlow, Yves Bas, Erika Berenguer, Christian Devenish, Filipe França, Stuart Marsden, Charlotte Smith, Alexander C. Lees   +8 more
wiley   +1 more source

Immunological memory to SARS‐CoV‐2 infection and COVID‐19 vaccines

Immunological Reviews, Volume 310, Issue 1, Page 27-46, September 2022., 2022
Abstract Immunological memory is the basis of protective immunity provided by vaccines and previous infections. Immunological memory can develop from multiple branches of the adaptive immune system, including CD4 T cells, CD8 T cells, B cells, and long‐lasting antibody responses.
Alessandro Sette, Shane Crotty
wiley   +1 more source