Results 21 to 30 of about 107 (94)

PLK4: Master Regulator of Centriole Duplication and Its Therapeutic Potential

open access: yesCytoskeleton, Volume 82, Issue 11, Page 747-763, November 2025.
ABSTRACT Centrosomes catalyze the assembly of a microtubule‐based bipolar spindle, essential for the precise chromosome segregation during cell division. At the center of this process lies Polo‐Like Kinase 4 (PLK4), the master regulator that controls the duplication of the centriolar core to ensure the correct balance of two centrosomes per dividing ...
Muhammad Hamzah   +2 more
wiley   +1 more source

Os Borges de Carvalhais, Senhores de Ferreiros, Avelãs de Cima e Ílhavo

open access: yesRevista de História da Sociedade e da Cultura, 2017
O vasto domínio senhorial frequentemente referido como “senhorio de Carvalhais” esteve na posse dos Borges e de seus descendentes desde meados do século XV até à reforma liberal.
Luís Seabra Lopes
doaj   +1 more source

The Effect of Exercise‐Induced Muscle Damage on Lower Limb Side Cut Biomechanics and Task Achievement in Male and Female Team Sport Athletes

open access: yesEuropean Journal of Sport Science, Volume 25, Issue 9, September 2025.
ABSTRACT The effect of exercise‐induced muscle damage (EIMD) on three‐dimensional side cut biomechanics and task achievement were assessed in 16 team sport athletes (eight males and eight females) who completed 45° side cuts before and 48 h after multidirectional running. Angular displacement and joint moments of the hip and knee, and GRF impulse (IGRF)
Chelsea L. Oxendale   +3 more
wiley   +1 more source

Effect of repeated bout effect induced by eccentric exercises on joint stiffness endurance in males

open access: yesPhysiological Reports, Volume 13, Issue 15, August 2025.
Abstract The purpose of this study was to investigate the effect of the repeated bout effect induced by eccentric exercises on joint stiffness endurance. Twelve males performed fatigue tasks (5 sets of 50 hopping) three times: first fatigue task on one side (FFT), second fatigue task on the same side 2 weeks after FFT (SFT), and opposite fatigue task ...
Soushi Mino   +3 more
wiley   +1 more source

Quo Vadis, Europa?

open access: yesPrim@ Facie, 2014
A chamada ‘crise do euro’ afeta as Instituições comunitárias europeias, pondo em xeque o processo democrático da União Europeia. As decisões são tomadas no âmbito das relações intergovernamentais, sob as ordens da Alemanha; na verdade, quem governa a ...
António José Avelãs Nunes
doaj   +4 more sources

Effect of static stretching duration on modulation of H‐reflex and tendon‐reflex excitability of the soleus muscle in young men

open access: yesPhysiological Reports, Volume 13, Issue 16, August 2025.
Abstract Stretching‐induced impairments of muscle performance are attributed to neural adaptations and mechanical changes. Inhibition of muscle spindle sensitivity appears to have long‐lasting effects after stretching. However, whether a dose–response relationship exists between stretching duration and muscle spindle sensitivity remains unclear.
Akira Saito, Takamasa Mizuno
wiley   +1 more source

The value of age of onset and family history as predictors of molecular diagnosis in a Swedish cohort of inherited retinal disease

open access: yesActa Ophthalmologica, Volume 103, Issue 3, Page 327-338, May 2025.
Abstract Purpose This study aimed to characterize clinical and genetic findings in a Swedish cohort with inherited retinal disease (IRD), identify predictors for achieving a molecular diagnosis and evaluate the effects of increased genetic testing over time.
Karl De Geer   +4 more
wiley   +1 more source

Sobre a utilidade da teoria na historiografia: mobilidade de conceitos e história comparada dos regimes políticos no século XX

open access: yesRevista Portuguesa de História, 2018
Procurando contrariar uma tendência de hostilidade ao debate teórico que, em parte, marcaria a historiografia em geral e a historiografia portuguesa em particular, reflete‑se, neste texto, sobre o modo como os paradigmas epistemológicos vigentes ao longo
João Paulo Avelãs Nunes
doaj   +1 more source

The acute effects of dynamic stretching on the neuromuscular system are independent of the velocity

open access: yesExperimental Physiology, Volume 110, Issue 3, Page 494-505, 1 March 2025.
Abstract This study examined the acute effects of dynamic stretching at different velocities on the neuromuscular system. Fourteen participants underwent four experimental sessions in random order: (1) control (lying at rest with the ankle in a neutral position); (2) slow velocity dynamic stretching (50 beats/min; SLOWDS); (3) moderate velocity dynamic
Denis César Leite Vieira   +4 more
wiley   +1 more source

[Recensão a] Francisco Carlos Palomanes Martinho, Marcello Caetano: uma biografia (1906‑1980)

open access: yesRevista Portuguesa de História, 2018
https://doi.org/10.14195/0870 ...
João Paulo Avelãs Nunes
doaj   +1 more source

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