Results 231 to 240 of about 169,954,449 (268)

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

In-Flight Self-Calibration of the STIX Grid Transmission. [PDF]

Sol Phys
Massa P, Volpara A, Stiefel MZ, Bilgili E, Degen M, Limousin O, Hurford GJ, Krucker S.   +7 more
europepmc   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Humans, but not zebra finches, produce spontaneously isochronous song through the lifespan. [PDF]

iScience
Bertolo M, Weiss MW, Peretz I, Sakata JT.   +3 more
europepmc   +1 more source

Effect of terahertz irradiation on DNA damage repair in living cells

FEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno, Shota Yamazaki, Hiromichi Hoshina, Masahiko Harata   +3 more
wiley   +1 more source

Stepping Up Enhanced Rate Calculations with EATR-Flooding. [PDF]

J Chem Theory Comput
Mazzaferro N, Peña Ccoa WJ, Cossio P, Hocky GM.   +3 more
europepmc   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

In Situ Characterization Reveals an Impaired Fibril Response to Loading Following Unloading during Early Achilles Tendon Healing. [PDF]

ACS Biomater Sci Eng
Silva Barreto I, Sharma K, Pierantoni M, Alim MA, Diaz A, Eliasson P, Isaksson H.   +6 more
europepmc   +1 more source

Consideration of Child and Family Information in Clinical Decision Making. [PDF]

Int J Lang Commun Disord
Sulek R, Schmedding-Bartley J, Bayley S.
europepmc   +1 more source