Results 121 to 130 of about 1,648,870 (357)
The gauge-invariant formulation of the local expansion rate driven by the local average density in an inhomogeneous universe [PDF]
, 2023 Masanori Tomonaga +2 more
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Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
BACKONE equation of state for Cis-1, 3, 3, 3-tetrafluoropropene (R1234ze(Z))
Vietnam Journal of Mechanics, 2018 This paper presents the study on the determination of the thermodynamic properties of Cis-1,3,3,3-tetrafluoropropene (R1234ze(Z)) with the BACKONE equation of state.
Phan Thi Thu Huong, Lai Ngoc Anh
doaj +1 more source
Breast cancer risk factors and demographic density among 12518 average-risk women in rural China [PDF]
, 2022 Huijiao Yan +7 more
openalex +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
FEBS Letters, EarlyView.The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber +7 more
wiley +1 more source
Assessment of Density Variations of Marine Sediments with Ocean and Sediment Depths
The Scientific World Journal, 2014 We analyze the density distribution of marine sediments using density samples taken from 716 drill sites of the Deep Sea Drilling Project (DSDP). The samples taken within the upper stratigraphic layer exhibit a prevailing trend of the decreasing density ...
R. Tenzer, V. Gladkikh
doaj +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
CONSIDERATIONS ON COMMON PRACTICAL APPLICATIONS OF NORMAL DISTRIBUTION [PDF]
Annals of the University of Petrosani: EconomicsIn the case of a large number of practical considerations, such as those related to the distribution coefficient of the population’s intelligence, the ratio between motivation and performance, but also the distribution of the average of an exam in the ...
CĂTĂLIN ILIE MITRAN
doaj