Results 221 to 230 of about 4,832,495 (330)
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
A Break from the Norm? Parametric Representations of Preference Heterogeneity for Discrete Choice Models in Health. [PDF]
Buckell J +3 more
europepmc +1 more source
Measuring intra‐axonal T2 in white matter with direction‐averaged diffusion MRI
Emilie T. McKinnon, Jens H. Jensen
openalex +2 more sources
Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde +3 more
wiley +1 more source
MACFIV: a novel framework for nonlinear causal inference in the body mass index-hypertension relationship with many weak and pleiotropic genetic instruments. [PDF]
Chen D, Wang Y, Shi D, Cao Y, Hu YQ.
europepmc +1 more source
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda +12 more
wiley +1 more source
Biological Breakthroughs and Drug Discovery Revolution via Cryo-Electron Microscopy of Membrane Proteins. [PDF]
Balasco Serrão VH.
europepmc +1 more source

