The ageing virus hypothesis: Epigenetic ageing beyond the Tree of Life
Viruses would age when the epigenetic signals they need to carry out their life cycle are degraded. Given the abundance and age of viruses, epigenetic aging of viruses would extend theories on the evolution of aging beyond cellular organisms, and encourage new models of viral dynamics and new anti‐viral therapies.
Éric Bapteste
wiley +1 more source
Avian Leucosis Virus-Host Interaction: The Involvement of Host Factors in Viral Replication
Avian leukosis virus (ALV) causes various diseases associated with tumor formation and decreased fertility. Moreover, ALV induces severe immunosuppression, increasing susceptibility to other microbial infections and the risk of failure in subsequent ...
Shuang Tang+3 more
doaj +1 more source
Can a patchy model describe the potential spread of West Nile virus in Germany? [PDF]
In 2018, West Nile Virus (WNV) was detected for the first time in Germany. Since the first detection, 36 human cases and 175 cases in horses and birds are detected. The transmission cycle of West Nile Virus includes birds and mosquitoes and -- as dead-end hosts -- people and horses.
arxiv
A mathematical model describing the localization and spread of influenza A virus infection within the human respiratory tract [PDF]
Within the human respiratory tract (HRT), viruses diffuse through the periciliary fluid (PCF) bathing the epithelium, and travel upwards via advection towards the nose and mouth, as the mucus escalator entrains the PCF. While many mathematical models (MMs) to date have described the course of influenza A virus (IAV) infections in vivo, none have ...
arxiv +1 more source
Isolation of Subgroup J Avian Leukosis Virus in Korea
Two subgroup J avian leukosis viruses (ALVs) were isolated from broiler breeder flocks, in which myeloid leukosis had occurred. The isolates could be classified as subgroup J ALV by the positive reaction in polymerase chain reaction (PCR) with primers specific for subgroup J ALV. Two isolates replicated in chicken embryo fibroblast (CEF) cells from the
Jae Hong Kim+3 more
openaire +3 more sources
Occurrence of different subgroups of avian leukosis virus in finnish poultry [PDF]
Ten Finnish breeding flocks were investigated for occurrence of avian leukosis virus and antibodies. The results show that field isolates representing all 4 main subgroups, A, B, C, and D, of avian leukosis virus have been identified. Antibodies to these subgroups are widespread in the country.
T. Estola, Karin Sandelin
openaire +3 more sources
Rodent models of tumours of the central nervous system
We describe the evolution of experimental systems, illustrated here in a timeline to show changing popularity over time. Starting with chemical and viral carcinogenesis, systems then developed into increasingly sophisticated genetically modified animal models.
Sebastian Brandner
wiley +1 more source
Virus or Avian Myeloblastic Leukosis
Abstract INTRODUCTION AVIAN leukosis is a complex of diseases which are not only of much economic importance, but which, in addition, comprise one category of virus-induced tumors. As a consequence, knowledge of the diseases is of fundamental interest in its bearing on the problem of cancer as a whole. Since the initial reports of the viral etiology
openaire +2 more sources
Posterior Basolateral Amygdala is a Critical Amygdaloid Area for Temporal Lobe Epilepsy
This study identifies the posterior basolateral amygdala (pBLA) as a critical nucleus in the regulation of temporal lobe epilepsy (TLE) within the amygdaloid complex. It highlights the distinct roles of both upstream and downstream neural circuits of the pBLA in modulating epileptic seizures.
Yan‐Hui Sun+11 more
wiley +1 more source
Epidemiological features and pathological study of avian leukosis in turkeys' flocks [PDF]
Aim: The purpose of this study was focused on the identification of tumor diseases in turkeys on the basis of a detailed description of epidemiological features, clinical signs, lesions, and histopathological changes.
Mourad Zeghdoudi+3 more
doaj +1 more source