Determination of the tumor virus b locus in turkish native chicken breeds [PDF]
Avian leukosis viruses (ALV) are retroviruses that can induce tumors in chicken. Typically, ALV is controlled through husbandry. However, genetic improvement and/or, selective breeding techniques, offer the unique possibility of true resistance.
Muhammet KAYA
doaj +1 more source
Alpharetroviral Vectors: From a Cancer-Causing Agent to a Useful Tool for Human Gene Therapy [PDF]
Gene therapy using integrating retroviral vectors has proven its effectiveness in several clinical trials for the treatment of inherited diseases and cancer.
Labenski, Verena +2 more
core +2 more sources
The chicken Tva cell surface protein, a member of the low-density lipoprotein receptor family, has been identified as an entry receptor for avian leukosis virus of classic subgroup A and newly emerging subgroup K.
Anna Koslová +13 more
doaj +1 more source
Isolation and analysis of a very virulent Marek’s disease virus strain in China [PDF]
BACKGROUND: A severe MD was broken out at a farm in Shandong, China, despite FC126 vaccination of the chickens at 1-day-old. The mortality of the flocks reached up to 38.3%.
Hongchao Ma +6 more
core +1 more source
Analysis of avian leukosis virus infections with an enzyme immunoassay [PDF]
An enzyme-linked immunosorbent assay (ELISA) for avian leukosis virus group-specific antigen was used to study infections with and shedding of avian leukosis virus in a commercial flock of chickens with a known high incidence of infection. Avian leukosis virus group-specific antigen was detected in serum or cloacal washings from 76% of a group of 100 ...
D P, Clark, R F, Ball, R M, Dougherty
openaire +2 more sources
The Genome of the Chicken DT40 Bursal Lymphoma Cell Line [PDF]
The chicken DT40 cell line is a widely used model system in the study of multiple cellular processes due to the efficiency of homologous gene targeting. The cell line was derived from a bursal lymphoma induced by avian leukosis virus infection.
Csabai, István +9 more
core +5 more sources
A recombinant avian leukosis virus subgroup j for directly monitoring viral infection and the selection of neutralizing antibodies. [PDF]
Avian leukosis virus subgroup J (ALV-J) has induced serious clinical outbreaks and has become a serious infectious disease of chickens in China. We describe here the creation of a recombinant ALV-J tagged with the enhanced green fluorescent protein ...
Qi Wang +10 more
doaj +1 more source
Keratin 6a marks mammary bipotential progenitor cells that can give rise to a unique tumor model resembling human normal-like breast cancer. [PDF]
Progenitor cells are considered an important cell of origin of human malignancies. However, there has not been any single gene that can define mammary bipotential progenitor cells, and as such it has not been possible to use genetic methods to introduce ...
Bu, W +10 more
core +2 more sources
Immune-Related Gene Expression in Two B-Complex Disparate Genetically Inbred Fayoumi Chicken Lines Following Eimeria maxima Infection [PDF]
To investigate the influence of genetic differences in the MHC on susceptibility to avian coccidiosis, M5.1 and M15.2 B-haplotype-disparate Fayoumi chickens were orally infected with live Eimeria maxima oocysts, and BW gain, fecal oocyst production, and ...
Aggarwal +54 more
core +3 more sources
RNA‐centric world of retroviruses: unravelling the molecular strategies of genomic RNA packaging
ABSTRACT Retroviruses constitute a unique group of RNA viruses that have profoundly influenced both evolutionary trajectories and biomedical research. Their ability to reverse transcribe and integrate into host genomes has shaped genomic architecture across species and contributed to our understanding of oncogenes, gene regulation, and RNA biology ...
Mohammad Abdullah Jehad +5 more
wiley +1 more source

