Results 11 to 20 of about 945 (85)

Development, Biological Characterization, and Immunological Evaluation of Virosome Vaccine against Newcastle Disease in Pakistan

BioMed Research International, Volume 2021, Issue 1, 2021., 2021
Newcastle disease (ND) is a highly fatal, infectious, viral disease, and despite immunization with live and inactivated vaccines, the disease is still endemic, causing heavy morbidity and mortality leading to huge economic losses to the poultry industry in Pakistan. Therefore, the present study was aimed for the first time in the country at using novel
Muhammad Hidayat Rasool, Asif Mehmood, Muhammad Saqalein, Muhammad Atif Nisar, Ahmad Almatroudi, Mohsin Khurshid, Yanjin Zhang   +6 more
wiley   +1 more source

Clinical, molecular and cytopathological characterization of a Newcastle disease virus from an outbreak in Baghdad, Iraq

Veterinary Medicine and Science, Volume 6, Issue 3, Page 477-484, August 2020., 2020
This study isolated NDV from an outbreak in North Baghdad, Iraq. The isolate was noted as velogenic by clinical experiment. Reverse transcriptase‐polymerase chain reaction (RT‐PCR) targeting the partial fusion‐protein gene of NDV genome, confirmed the virus.
Ahmed M. Al‐Shammari, Mohammed A. Hamad, Murtadha A. AL‐Mudhafar, Khansaa Raad, Aeser Ahmed   +4 more
wiley   +1 more source

Genomic and Pathogenic Characteristics of Virulent Newcastle Disease Virus Isolated from Chicken in Live Bird Markets and Backyard Flocks in Kenya

International Journal of Microbiology, Volume 2020, Issue 1, 2020., 2020
Newcastle disease (ND) causes significant economic losses in the poultry industry in developing countries. In Kenya, despite rampant annual ND outbreaks, implementation of control strategies is hampered by a lack of adequate knowledge on the circulating and outbreak causing‐NDV strains. This study reports the first complete genome sequences of NDV from
Irene N. Ogali, Paul O. Okumu, Erick O. Mungube, Jacqueline K. Lichoti, Stephen Ogada, Grace K. Moraa, Bernard R. Agwanda, Sheila C. Ommeh, Todd R. Callaway   +8 more
wiley   +1 more source

In vitro and in vivo evaluation of the cyclophosphamide effect along with oncolytic Newcastle disease virus (NDV): An animal preclinical research

Malignancy Spectrum, Volume 2, Issue 1, Page 13-25, March 2025.
This article explores combining Newcastle disease virus (NDV) with chemotherapy for treating breast cancer. Results show promising effects, including tumor suppression and improved patient prognosis without harming healthy tissues. The study suggests that NDV combined with chemotherapy could be a valuable treatment option, highlighting its potential ...
Mohammad Reza Foroughi‐Gilvaee, Alireza Jahandideh, Mohammad Faranoush, Reza Nekouian   +3 more
wiley   +1 more source

Comparative analysis of early immune responses induced by two strains of Newcastle disease virus in chickens

MicrobiologyOpen, Volume 8, Issue 4, April 2019., 2019
In this study, we showed that the GD NDV strain replicated more efficiently in most chicken tissues than the F48E9 strain. The higher levels of virus replication of the GD strain may be associated with a stronger innate immune response compared with the F48E9 strain. Abstract Newcastle disease, caused by virulent strain of Newcastle disease virus (NDV),
Tingting Zhang, Mengting Ren, Chenggang Liu, Liwen Xu, Fangfang Wang, Zongxi Han, Yuhao Shao, Deying Ma   +7 more
wiley   +1 more source

Molecular Characterization and Phylogenetic Analysis of Velogenic NDV Genotype VII Isolated From an Outbreak in Genotype II‐Vaccinated Poultry Flocks of the Southern Region of Pakistan

BioMed Research International, Volume 2025, Issue 1, 2025.
Despite the administration of multiple doses of the Newcastle disease virus (NDV) vaccine, a high mortality rate (20%–40%) due to NDV was observed in the southern region of Pakistan. In the current study, clinical samples were obtained from affected areas with NDV infection.
Johar Hussain, Muhammad Sohail, Aqeel Ahmad, Faiz Muhammad, Syed Khurram Fareed, Shakeel Ahmed Khan, Iftikhar Ahmed   +6 more
wiley   +1 more source

Avian influenza overview November 2018 – February 2019

EFSA Journal, Volume 17, Issue 3, March 2019., 2019
No human infections due to highly pathogenic avian influenza (HPAI) A(H5N8) or A(H5N6) viruses ‐ detected in wild birds and poultry outbreaks in Europe ‐ have been reported so far and the risk of zoonotic transmission to the general public in Europe is considered very low.
European Food Safety Authority, European Centre for Disease Prevention and Control, European Union Reference Laboratory for Avian influenza, Cornelia Adlhoch, Thijs Kuiken, Isabella Monne, Paolo Mulatti, Krzysztof Smietanka, Christoph Staubach, Irene Muñoz Guajardo, Francesca Baldinelli   +10 more
wiley   +1 more source

Newcastle disease virus co‐expressing interleukin 7 and interleukin 15 modified tumor cells as a vaccine for cancer immunotherapy

Cancer Science, Volume 109, Issue 2, Page 279-288, February 2018., 2018
A recombinant NDV virus co‐expressing IL15 and IL7 was generated. Tumor cells modified with this recombinant virus exhibited much strong antitumor responses both in vitro and in vivo. Interleukin 15 (IL15) and IL7 are two cytokines essential for T cell development and homeostasis.
Xiaojing Xu, Qing Sun, Yu Mei, Yonghao Liu, Lixiang Zhao   +4 more
wiley   +1 more source

Nucleotide sequence characterization, amino acid variations and 3D structural analysis of HN protein of the NDV VIId genotype

Veterinary Medicine and Science, Volume 10, Issue 4, July 2024.
Graphical Abstract: • Nucleotide and amino acid sequence characterization of NDV HN protein. • Three‐dimensional and molecular dynamics simulation analysis. • Applying immunoinformatic analysis for finding linear and conformational antigenic epitopes.
Amin Tavassoli, Safoura Soleymani, Mohammad Reza Housaindokht   +2 more
wiley   +1 more source

Spatiotemporal Patterns and Risk Factors for Newcastle Disease Virus among Chickens in a Tanzania Live Bird Market

Transboundary and Emerging Diseases, Volume 2024, Issue 1, 2024.
Village poultry plays a vital role in providing essential nutrition and income for rural communities in Africa. In this context, poultry are often traded through live bird markets (LBMs), which serve as central trading hubs where producers connect with traders and consumers, facilitating the flow of poultry products along the value chain.
John B. Tsaxra, Rodrigo A. Gallardo, Celia Abolnik, Augustino A. Chengula, Peter L. M. Msoffe, Amandus P. Muhairwa, Thandeka Phiri, James R. Mushi, Nadira Chouicha, Esther L. Mollel, Huaijun Zhou, Terra R. Kelly, Karima Al Salihi   +12 more
wiley   +1 more source