Results 81 to 90 of about 1,070,723 (284)

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Berryman Institute Professional and Program Awards

open access: yesHuman-Wildlife Interactions, 2018
The Berryman Institute (BI) is a national organization based in the Department of Wildland Resources at Utah State University. We are dedicated to improving human–wildlife relationships and resolving human–wildlife conflicts through teaching, research ...
Terry A. Messmer
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Ulusal ve Uluslararası Ödüllü Ebelik Temalı Dizi ve Filmlerde Ebe İmajının İncelenmesi

open access: yesEbelik ve Sağlık Bilimleri Dergisi
Amaç: Bu çalışmada ulusal ve uluslararası ödüllü ebelik temalı dizi ve filmlerde ebe imajının incelenmesini amaçlamaktadır. Araştırmada içerik çözümlemesi yöntemine başvurulmuştur.
Bihter Akın, Bilgesu Çelik
doaj  

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Mahatma Gandhi International Award for Reconciliation and Peace

open access: yes, 2022
Dr. Brigalia Bam received the Mahatma Gandhi International Award for Reconciliation and Peace in 26 August 2013.The award reflects recognition and honor of outstanding work as Chairperson of the South African Independent Electoral Commission and ...

core  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Children's Picture Books. An Overview

open access: yesRATE Issues, 2019
This article aims at presenting a series of famous, beautiful picture books for children, considered of great literary value worldwide today. Moreover, the article will analyze the suggested titles in great detail, starting from the covers, format and ...
Carina Branzila, Mihaela Gazioglu
doaj  

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