Results 171 to 180 of about 215,706 (302)
Boosting Biomedical Research Capacity: The Role of INBRE-Supported Core Facility Vouchers in IDeA States. [PDF]
Lessard LM, Duncan MK.
europepmc +1 more source
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Continuity of State Awards of the Republic of Tuva after its Incorporation into the USSR
Introduction: The article is devoted to the issue of the continuity of the legal regime of awards of the Tuvan People’s Republic in the conditions of the TNR’s entry into the USSR in 1944.Methodology and materials: The article is based on the sources and
A. A. Elaev
doaj
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
Do Intramural Career Development Programs Provide an Advantage to Rehabilitation Scientists Applying for Merit-Review Scientific Funding? A Retrospective Cohort Study. [PDF]
Fraser JJ, Schwinder EJ, Spaniol ED.
europepmc +1 more source
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
openaire +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Small Business Grants Awarded by the National Institutes of Health for Rhinologic Diseases, 1985-2024. [PDF]
Birkenbeuel J +7 more
europepmc +1 more source
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source

