Results 111 to 120 of about 8,121 (341)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Multitasking, Learning, and Incentives: A Cautionary Tale [PDF]

open access: yes
We develop a multi-period, multi-task principal-agent model in which neither the principal nor the agent knows the mapping from actions to outputs. The agent can learn about the production function over time by exerting effort and observing output.
Richard T. Holden, Roland G. Fryer, Jr
core  

Strengthening nutrition incentive and produce prescription projects

open access: yesJournal of Agriculture, Food Systems, and Community Development
The Gus Schumacher Nutrition Incentive Program (GusNIP), funded by the U.S. Department of Agriculture (USDA) National Institute of Food and Agriculture (NIFA), is a federal program designed to address financial barriers to fruit and vegetable (FV ...
Sarah Stotz   +7 more
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Paying to Learn: The Effect of Financial Incentives on Elementary School Test Scores [PDF]

open access: yes
Policymakers and academics are increasingly interested in applying financial incentives to individuals in education. This paper presents evidence from a pay for performance program taking place in Coshocton, Ohio.
Eric P. Bettinger
core  

Short-Term Incentives: Top Down or Bottom Up?

open access: yes, 2011
This article positions the short-term incentive plan in relation to the other four pay elements: salary, employee benefits, perquisites (executive benefits) and long-term incentives. Short-term incentives typically have a measurement period of 1 year or
Bruce R. Ellig
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Stock options and managerial incentives to invest [PDF]

open access: yes
We examine the effect of stock options on managerial incentives to invest. Our chief innovation is a model wherein firm value and executive decisions are endogenous.
Nohel, Tom, Steven Todd
core  

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