A Round Up of the Prize Winning Papers From the <i>European Journal of Vascular and Endovascular Surgery</i> 2024. [PDF]
EJVES Vasc ForumÁlvarez Marcos F +2 more
europepmc +1 more source
FEBS Open Bio, EarlyView.The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida +6 more
wiley +1 more source
Science and prizes : A case for rethinking the criteria for prizes in science (and for rewarding important discoveries in bacterial physiology). [PDF]
EMBO RepNorris V.
europepmc +1 more source
Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes
FEBS Open Bio, EarlyView.We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde +3 more
wiley +1 more source
Clinical Group Students/Trainees Essay Contest Winner "Here Versus There: A Summer Vacation Story". [PDF]
Am J Trop Med HygDrobish I, Nair J, Ackerman H.
europepmc +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Artificial Intelligence awarded two Nobel Prizes for innovations that will shape the future of medicine. [PDF]
NPJ Digit MedLi B, Gilbert S.
europepmc +1 more source
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
NIDDK at 75 Years of Age: Great Triumphs but Concerns for Its Longevity. [PDF]
Diabetes CareKahn SE +4 more
europepmc +2 more sources