Results 71 to 80 of about 143,027 (290)

Ethnic Differences in the Association Between SOD2 rs4880 and Hepatotoxicity in Pediatric Acute Lymphoblastic Leukemia: A Report From the REDIAL Consortium

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Treatment‐associated hepatotoxicity (TAH) is a common complication of pediatric acute lymphoblastic leukemia (ALL) treatment, but genetic risk factors remain poorly understood. We evaluated the SOD2 rs4880 variant in 544 children with ALL at Texas Children's Hospital. After adjusting for demographic and clinical covariates, the rs4880 C allele
Emily J. Mason, John P. Woodhouse, Joanna S. Yi, M. Monica Gramatges, Olga A. Taylor, Veronica A. Morales, Shalini Dhamodharan, Marley Roberts, Karen R. Rabin, Philip J. Lupo, Michael E. Scheurer, Van Huynh, Steven D. Mittelman, Etan Orgel, Austin L. Brown   +14 more
wiley   +1 more source

Science in the Trap of Fraud and Corruption

Communications, 2017
The expression pathological science was introduced by I. Langmuir already in 1953. Since that time the investments into science and competition have been increasing and, consequently, the ground for scientific misconduct continues to expand.
Stefan Luby, Martina Lubyova, Ladislav E. Roth   +2 more
doaj   +1 more source

Therapeutic Apheresis for Intravenous Methylprednisolone‐Refractory Neuromyelitis Optica Spectrum Disorder: Clinical and Radiological Outcomes in a Single‐Center Case Series

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi, Daisuke Katagiri, Takeyuki Watadani, Shunichi Matsuda, Hiroshi Kaneko, Noritoshi Arai   +5 more
wiley   +1 more source

Classical Cooperative Learning Model for Reading Classic Literature: Enhancing Student Independence through Self-Regulation

Izdihar
This study aimed to analyze the cooperative learning model developed by teacher at the Miftahul Midad Islamic Boarding School  Indonesia, which combines classical learning to enhance students' ability to read classical texts and foster their ...
Umar Manshur, Nur Hadi, Mowafg Abrahem Masuwd   +2 more
doaj   +1 more source

Carbonic mineral waters of eastern Slovakia and possibilities of their usage [PDF]

Acta Montanistica Slovaca, 2008
Mineral water is water containing minerals or other dissolved substances that alter its taste or give it a therapeutic value.Slovakia is a small country, which is not rich in the raw materials.
Lenka Pixová, Stela Hanigovská, Katarína Verčimáková   +2 more
doaj  

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Beyond Bedlam: How Consumers and Brands Alike Are Playing the Web

GfK Marketing Intelligence Review, 2014
Effective social brand engagement can result from marketers “getting in the game” by playing with consumers. Play can take many different forms and can refer to different aspects. It can produce winners and losers, for example when marketers conquer the
Deighton John, Kornfeld Leora
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

The Nature of Inventive Activities: Evidence from a Data-Set of the Okouchi Prizes and a Comparison with the R&D 100 Awards [PDF]

This paper conducts preliminary analysis on technological innovation by using prize and award data sets: the Okouchi Prizes and the R&D 100 Awards. It aims to outline longitudinal patterns of award-winning industries, organizational type, and inter ...
Hoshino, Yusuke, Shimizu, Hiroshi
core  

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source