Results 31 to 40 of about 3,406,321 (226)

CFD analysis to understand the flow behaviour of a single stage transonic Axial flow compressor [PDF]

open access: yes, 2013
This paper comprises the Computational Fluid Dynamic (CFD) analysis to investigate the flow behaviour of a high speed single stage transonic axial flow compressor.
Shobhavathy, MT, Premakara , Hanoca
core  

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Determining the influence of roughness and tip clearance on the axial multistage compressor characteristics

open access: yesАвіаційно-космічна техніка та технологія
The operation of gas turbine engines inevitably increases the blade roughness and tip clearance in multistage axial compressors. The result is an increase in its thermogasodynamic parameters. The reason for the increase in the roughness of the blades and
Vadym Datsenko
doaj   +1 more source

The investigation of absolute flow non-uniform velocity distributions influence at the centrifugal compressor axial radial impeller inlet using numerical calculation methods in ANSYS CFX [PDF]

open access: yesE3S Web of Conferences, 2019
Currently, methods of numerical modelling are widely used. They are especially widely used in the design of turbo compressors. For the specific task of designing new flowing parts of a centrifugal compressor, it is not recommended to deviate from the ...
Rakhmanina L.A.   +4 more
doaj   +1 more source

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

open access: yesFEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

Microstructural Evolution and Vacancy Defect Formation in Mn–Mo–Ni RPV Steel Under Low Cycle Fatigue: Insights From EBSD and PALS

open access: yesAdvanced Engineering Materials, EarlyView.
Low‐cycle fatigue damage in Mn–Mo–Ni reactor pressure vessel steel is examined using a combined electron backscatter diffraction and positron annihilation lifetime spectroscopy approach. The study correlates texture evolution, dislocation substructure development, and vacancy‐type defect formation across uniform, necked, and fracture regions, providing
Apu Sarkar   +2 more
wiley   +1 more source

Performance and Stall Margin Evaluation of Axial Slot Casing Treatment in a Transonic Multistage Compressor

open access: yesAerospace
Adverse pressure gradients are intrinsic to compressor flow behavior and are further intensified by secondary effects associated with rotor tip clearance flow interactions. Tip clearance generates leakage flow, which leads to the formation of tip leakage
Pedro Seiti Endo   +4 more
doaj   +1 more source

Thermomechanical Fatigue and Creep–Fatigue Interaction of Inconel 718 Additively Manufactured by Laser Beam Powder Bed Fusion

open access: yesAdvanced Engineering Materials, EarlyView.
Thermomechanical fatigue tests of laser beam powder bed fusion (PBF‐LB) Inconel 718 show that the additively manufactured material reaches almost the lifetimes of conventionally‐rolled material under no‐dwell conditions. Introducing dwell times at the maximum temperature markedly reduces the lifetimes due to pronounced grain boundary sliding associated
Stefan Guth   +6 more
wiley   +1 more source

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