Results 51 to 60 of about 17,797 (259)

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Development of rear‐impeller axial flow blood pump for realization of axial flow blood pump installed at aortic valve position [PDF]

open access: yesArtificial Organs, 2019
AbstractIn this study, rear‐impeller axial flow blood pumps (RIAFBP) were developed to realize a trans‐valve axial ventricular assist device (VAD) which consists of the latter blood pump and a polymer monomembrane aortic valve, such as the jellyfish valve.
Eiji Okamoto   +5 more
openaire   +3 more sources

Prediction of Myasthenia Gravis Worsening: A Machine Learning Algorithm Using Wearables and Patient‐Reported Measures

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is a rare disorder characterized by fluctuating muscle weakness with potential life‐threatening crises. Timely interventions may be delayed by limited access to care and fragmented documentation. Our objective was to develop predictive algorithms for MG deterioration using multimodal telemedicine data ...
Maike Stein   +7 more
wiley   +1 more source

Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani   +8 more
wiley   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling   +16 more
wiley   +1 more source

Current Tracking Adaptive Control of Brushless DC Motors

open access: yesInternational Journal of Adaptive Control and Signal Processing, EarlyView.
In this paper, the current tracking for Brushless Direct Current motors is approached considering uncertainty in the parameters of the motor's model. An adaptive control scheme to compensate electrical parameters uncertainty is proposed without requiring any knowledge of the mechanical parameters.
Fernanda Ramos‐García   +3 more
wiley   +1 more source

Manufacturing Continuous Fiber‐Reinforced Printing Filaments: Development of a Post‐Consolidation Unit

open access: yesAdvanced Engineering Materials, EarlyView.
A novel, temperature‐controlled post‐consolidation unit is developed to test its potential to improve the melt impregnation process used to manufacture continuous fiber‐reinforced filaments for additive manufacturing of high‐performance thermoplastics.
Daniel Beermann   +2 more
wiley   +1 more source

INDIRECT METHODS OF MEASURING FLОW RATE AND PRESSURE DROP OF ROTARY BLOOD PUMPS

open access: yesВестник трансплантологии и искусственных органов, 2015
The article describes complex software to calculate the main parameters of the axial pump (pressure drop and flow rate) on the basis of an analysis of its technical characteristics (current consumption and pump speed).
G. P. Itkin   +3 more
doaj   +1 more source

Cavitation Tests on an Axial Flow Pump

open access: yesBulletin of JSME, 1959
Cavitation tests on an axial flow pump were made over a wide range of operating conditions. Through these tests, the aspects of cavitation in the impeller were observed with a strobolight and variation of the pump characteristics was studied. A parameter σs to represent the suction condition was introduced to give the cavitation limits for any flow ...
Chikanobu HORIE, Kyoji KAWAGUCHI
openaire   +2 more sources

On‐Demand Activation of Thin Alginate Shell Encapsulated Volatile Liquid for Untethered Pneumatic Soft Actuation

open access: yesAdvanced Engineering Materials, EarlyView.
Phase‐changing liquids enable untethered pneumatic actuation in soft robotics but suffer from volatility and storage challenges. This work reports a simple method to encapsulate Novec 7000 within micron‐thin alginate shells via in situ injection and ionic crosslinking.
Rayan A. M. Basodan   +3 more
wiley   +1 more source

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