Results 111 to 120 of about 2,349,133 (334)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

A Note on Transverse Axial Vector and Vector Anomalies in U(1) Gauge Theories

open access: yes, 2003
The transverse axial vector and vector anomalies in four-dimensional U(1) gauge theories studied in [10] is reexamined by means of perturbative methods. The absence of transverse anomalies for both axial vector and vector current is verified.
't Hooft   +17 more
core   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The Mechanical Impact of Aerodynamic Stall on Tunnel Ventilation Fans

open access: yesInternational Journal of Rotating Machinery, 2012
This paper describes work aimed at establishing the ability of a tunnel ventilation fan to operate without risk of mechanical failure in the event of aerodynamic stall.
A. G. Sheard, A. Corsini
doaj   +1 more source

Chiral sound waves in strained Weyl semimetals

open access: yes, 2019
We show that a strained wire of a Weyl semimetal supports a new type of gapless excitation, the chiral sound wave (CSW). It is a longitudinal charge density wave analog to the chiral magnetic wave predicted in the quark-gluon plasma but driven by an ...
Chernodub, M. N.   +1 more
core   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Family Structure of Leptons and Their Currents of an Axial Vector Nature [PDF]

open access: yes, 2005
Each of neutrinos has a non - zero mass and regardless of whether it is a Dirac or a Majorana mass, can possess both anapole and electric dipole moments.
Sharafiddinov, Rasulkhozha S.
core   +4 more sources

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Structural Performance of Columns with Glass Fiber-Reinforced Polymer Bars Under Axial Compression

open access: yesFibers
Corrosion continues to be a major challenge affecting the service life, safety and durability of steel-reinforced concrete (RC) structures. The deterioration of steel not only reduces structural capacity but also increases long-term maintenance costs. To
Trupti Amit Kinjawadekar   +2 more
doaj   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy