Results 121 to 130 of about 1,497,791 (338)

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

On The Effect Of Axial Dispersion In The Numerical Simulation Of Fast Cycling Adsorption Processes [PDF]

open access: yes, 2005
The Effects Of Axial Dispersion In The Numerical Simulation Of Fast Cycling Adsorption Processes Were Studied. The Main Objectives Are: (1) To Re-Examine The Observation Of Alpay [1] On The Effect Of Axial Dispersion On The Oxygen Purity For A 1.0 M ...
T. G. Chuah , T. G. Chuah   +4 more
core  

Axial dispersion in segmented gas-liquid flow: Effects of alternating channel curvature

open access: yes, 2010
The effects of channel curvature on the axial dispersion in segmented gas-liquid flows are studied computationally in a two-dimensional setting using a finite-volume/front-tracking method.
Metin Muradoglu, Muradoglu, Metin
core   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

Axial dispersion of liquid in packed beds.

open access: yes, 1966
Douglas, W. (Supervisor)The axial dispersion of liquid in a fixed bed of dry randomly packed Raschig rings was investigated in a 1-foot diameter column for three sizes of packing: 0.5, 1.0 and 1.5-inch.
Khanna, Ram Tirth
core  

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

Modeling of protein breakthrough performance in cryogel columns by taking into account the overall axial dispersion.

open access: yes, 2009
A model considering the overall axial dispersion for describing protein adsorption and breakthrough in monolithic cryogel beds has been developed.
Junxian Yun   +7 more
core   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

open access: yesFEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro   +1 more
wiley   +1 more source

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