Results 121 to 130 of about 885,795 (303)

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

FEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph, Andrea B. Pham, Kiara E. Bornes, Razan H. Hammad, Chelsea A. Rousseve‐Ross, Thomas M. Huckaba, Terry J. Watt, Tasha B. Toro   +7 more
wiley   +1 more source

Study on the Influence of Mechanical Spindle Axial Movement based on ADAMS Simulation Analysis

Jixie chuandong, 2017
Based on a gear tooth fracture case,which is caused by diesel engine crankshaft axial movement. Aiming at the situation that it’s difficult to simulate this fault by experiment,the displacement and movement type can’ t be control.
Jia Yang, Wu Yalong, Wang Zhongmin, Mao Zhiwei, Zhang Jinjie   +4 more
doaj  

Radial Displacement Sensor for Measuring Rotor Axial Displacement

DEStech Transactions on Engineering and Technology Research, 2017
JUN MIN ZHOU, ZHONG GUO BIAN, SHU QIN LIU   +2 more
openaire   +2 more sources

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

Axial Spondyloarthritis

, 2016
Axial spondyloarthritis is the commonest inflammatory arthritis affecting the spine. Typically first presenting to a variety of primary and secondary care professionals, the high global disease burden of this condition has created a need for increased ...

core  

Cementless long-stem fixation in periprosthetic clamshell fracture: a biomechanical investigation

Frontiers in Bioengineering and Biotechnology
ObjectiveTo investigate the biomechanical strength of cementless long-stem fixation for the treatment of periprosthetic clamshell fracture.MethodsEighteen Sawbones artificial femur models were used and divided into three groups.
Lingqi Zhu, Li Xie, Mingchang He, Jianyun Miao, Liang Zhou, Lianshui Huang, Hui Liu, Wei Xie, Wenliang Zhai   +8 more
doaj   +1 more source

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

FEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer, Pawel Rubach, Zbigniew Dauter, Wojciech Dec, Dariusz Brzezinski, Marta Kulik, Wladek Minor, Mariusz Jaskolski   +7 more
wiley   +1 more source

Analysis of Traveling Wave and Combined Site Effect of Long-Span Upper-Bearing Concrete-Filled Steel Tubular Arch Bridge

Advances in Civil Engineering
In order to study the traveling wave effect and combined site effect of long-span steel tube concrete-filled arch bridge, a 400-m span bridge of the same type is taken as an example, and a large-mass time-history analysis method with multipoint input of ...
Zite Li, Genhui Wang, Jiang Fan, Yue Jian, Yongliang Zhang   +4 more
doaj   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source