Results 51 to 60 of about 4,397,066 (309)
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
Investigation of the Unsteady Flow Generated by an Axial Fan: Experimental Testing and Simulations
International Journal of Rotating Machinery, 2005 The unsteady flow measurement of a large axial fan with diameter 1.829m (6 ft) has been carried out. The complex flow field generated by the fan is investigated through experimental testing and CFD/FEA simulation.
R. S. Amano +3 more
doaj +1 more source
Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley +1 more source
Propulsion and Power Research, 2020 The present study introduces an innovative aerodynamic redesign of an axial flow fan based on constant diffusion factor and radial equilibrium. All input design parameters such as mass flow rate, hub to tip ratio, aspect ratio, tip diameter and angular ...
Ali Shahsavari, Mahdi Nili-Ahmadabadi
doaj +1 more source
Heterotropic regulation and negative homotropic cooperativity
FEBS Open Bio, EarlyView.We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source
Computers and Electronics in Agriculture, 2019 Air assisted sprayers are currently used for the applications of plant protection products in fruit trees and vineyards. However, the use of these equipment carries a high environmental risk, mainly owing to the generation of airborne spray drift in the ...
R. Salcedo +7 more
semanticscholar +1 more source
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
Aging and Cancer, EarlyView.NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
The Design of Special Singlewinding Twospeed Motor for Contrarotating Axialflow Fan
Journal of Harbin University of Science and Technology, 2020 Aiming at the problems of the pressure rise and power imbalance and the problem of serious reduction of efficiency when the contrarotating axial flowfan deviates from the rated operating point,the twostage drive motor of the fan is studiedIn this paper ...
MENG Dawei +3 more
doaj +1 more source
Choroid Plexus Enlargement and USPIO‐Based Inflammatory Feature in Cerebral Small Vessel Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective The choroid plexus (CP) is a key component of the blood–cerebrospinal fluid barrier (BCSFB), but its mechanism of action in cerebral small vessel disease (CSVD) remains unclear. This study investigated CP volume (CPV) alterations and their association with conventional imaging markers in CSVD and explored the underlying role of ...
Yongqiang Qu +11 more
wiley +1 more source
EAA Benchmark for an axial fan
, 2020 ĂWe present detailed numerical results of the EAA benchmark case of an axial fan. Thereby, we aim to present the whole aeroacoustic simulation process for a successful computation of the flow and acoustic signature of an axial fan: (1) Meshing approach for the CFD simulation; (2) Turbulence modeling; (3) CFD convergence study; (4) Evaluation of the ...
Kaltenbacher, Manfred, Schoder, Stefan
openaire +1 more source