Dual-surface aberration-increasing lenses versus single-vision lenses in non-myopic children: a randomized clinical trial. [PDF]
Lu W +10 more
europepmc +1 more source
PDIA6–SCD1 Axis Rewires Lipid Metabolism to Drive Gastric Cancer Progression
Protein disulfide isomerase A6 (PDIA6) is identified as an oncogenic driver in gastric cancer. PDIA6 directly binds and stabilizes SCD1 by limiting its ubiquitin–proteasome‐mediated degradation, thereby sustaining monounsaturated fatty acid (MUFA)‐enriched lipid homeostasis and lipid metabolic reprogramming.
Zhen Tian +13 more
wiley +1 more source
Tunable Bessel beam two-photon fluorescence microscopy for high-speed volumetric imaging of brain dynamics. [PDF]
Li MJ +8 more
europepmc +1 more source
Here we developed Am@SExo, a dual‐functional engineered exosome that coordinates CD47–SIRPα checkpoint blockade with Arg1 mRNA–mediated metabolic reprogramming. Surface SIRPα promotes recognition of apoptotic cells and plaque targeting, while Arg1 expression enhances arginine–ornithine metabolism, Rac1 activation, and actin remodeling in macrophages ...
Danwen Zheng +17 more
wiley +1 more source
Cavitation-enhanced carbonation for nano-ZnO synthesis via an ultrasonic-jet coupled reactor: Machine learning prediction and multi-objective optimization using a genetic algorithm. [PDF]
Guo J, Yu H, Wang D, Fan L.
europepmc +1 more source
An intracellular magneto‐mechanical platform utilizing MSC‐targeted nanomotors is developed. After intra‐articular delivery, these nanomotors target endogenous BMSCs and are actuated within lysosomes to execute trans‐planar rotational‐bouncing motions under a rotating‐fluctuating 3D magnetic field, generating amplified mechanical stimulation.
Zhenguang Li +7 more
wiley +1 more source
Research on the dust transportation law and cyclone air curtain dust control technology of coalface. [PDF]
Zhao X, Wang H, Wang J.
europepmc +1 more source
Hair Follicle Seedling Cryomicroneedles from Hierarchical Microfluidic Organoid on a Chip
In this paper, a hierarchical microfluidic chip is developed to produce uniform hair follicle organoids (HFOs) in cryomicroneedles. Cryopreservation agents encapsulate HFOs, preserving viability and hair growth potential. The cryomicroneedles enable simple intradermal transplantation with good skin penetration.
Xinyue Cao +3 more
wiley +1 more source
Cataract Surgery in Congenital Colobomatous Microphthalmia Associated With Intraorbital Cyst in an Adult. [PDF]
Zhao YE, Zhang F, Wang D.
europepmc +1 more source
Multiferroic order parameters – polarization, magnetization, and ferroelastic strain – are positioned as dynamic design variables for batteries. Their mechanistic roles, practical tuning through fabrication and external fields, and ferroic‐resolved characterization routes are unified into a closed‐loop framework, revealing how coupled ferroic responses
Jiaqi Su +13 more
wiley +1 more source

