Results 91 to 100 of about 75,134 (266)

Study on the Time-Varying Stiffness Characteristics of Four-Point Contact Ball Bearings

open access: yesLubricants
This paper takes a four-point contact ball bearing of a wind turbine as the research object, analyzes the force and deformation relationship under the combined action of axial load and radial load, obtains the load distribution of rolling elements, and ...
Runlin Chen   +5 more
doaj   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

The effect of the design of the orthosis on the axial load transmission of two flexion abduction orthoses used in treating congenital hip dysplasia. [PDF]

open access: yesHeliyon, 2022
Schwanitz von Keitz P   +7 more
europepmc   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Impact Load Characteristics of Large-Scale Trans-Medium Vehicles during High-Speed Oblique Water Entry

open access: yes水下无人系统学报
To investigate the impact load characteristics of large-scale trans-medium vehicles during high-speed oblique water entry, a three-dimensional unsteady numerical calculation model of high-speed oblique water entry of the trans-medium vehicles was ...
Tongyun ZHANG   +5 more
doaj   +1 more source

In vivo measurements of spinal stiffness according to a stepwise increase of axial load. [PDF]

open access: yesEur J Appl Physiol, 2021
Glaus LS   +4 more
europepmc   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

open access: yesFEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi   +6 more
wiley   +1 more source

Experimental Study to Determine the Development of Axial Stiffness of Wood Screws with Increasing Load Cycles

open access: yesBuildings
123 withdrawal tests were conducted to investigate the change in axial stiffness of fully threaded screws under axial loading and up to four loading cycles.
Sebastian Egner, Philipp Dietsch
doaj   +1 more source

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