Results 21 to 30 of about 75,134 (266)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Load responses of semirigid and semiflexible segment joints in submerged floating tunnels

Applied Ocean Research
Submerged floating tunnels (SFTs) have garnered significant attention because of their application potential. The joints between segments of a submerged floating tunnel are critical and vulnerable components of the overall structure.
Linjian Wu, Zhouyu Xiang, Mingwei Liu, Zhonghao Wang, Bo Liu, Yunfeng Xiao   +5 more
doaj   +1 more source

Axial-loaded Magnetic Resonance Imaging in the Diagnosis of Static Disorders of the Lumbar Spine

Гений oртопедии, 2020
Introduction The diagnosis of spinal statics disorders requires a study conducted both with and without axial load. Standard multislice computed tomography (MSCT) and magnetic resonance imaging (MRI) are limited to the examination of the patient in the ...
Alexandr V. Bazhin, Elena A. Egorova, Dmitry A. Lezhnev, Aleksandr Yu. Vasilyev, Viktor P. Truten, Margarita V. Smyslenova   +5 more
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Axial Load Monitoring for Concrete Columns Using a Wearable Smart Hoop Based on the Piezoelectric Impedance Frequency Shift: A Feasibility Study

Advances in Civil Engineering, 2020
Concrete columns are critical in supporting the weight of an entire structural frame and also play a key role in force transferring among structural members.
Yabin Liang, Zhicheng Ye, Qian Feng
doaj   +1 more source

Biomechanical Study of Intramedullary Versus Extramedullary Implants for Four Types of Subtrochanteric Femoral Fracture

Orthopaedic Surgery, 2022
Objectives To compare the biomechanical performance of proximal femoral nail anti‐rotation (PFNA), the “upside‐down” less invasive plating system (LISS), and proximal femoral locking plate (PFLP) in fixing different fracture models of subtrochanteric ...
Jie Wang, Haobo Jia, Xinlong Ma, Jianxiong Ma, Bin Lu, Haohao Bai, Ying Wang   +6 more
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Effect of Wind Loading Pattern on Shear Lag Phenomenon in Framed-Tube Building [PDF]

Journal of Rehabilitation in Civil Engineering
High-rise tubular buildings experience the shear lag phenomenon due to wind load. This phenomenon results in tension in upper storey columns that may adversely affect building stability.
Ashish Singh, Piyush Gaikwad, Sasankasekhar Mandal   +2 more
doaj   +1 more source

Experimental Study and Finite Element Modelling of Squat Shear Walls under Combined Cyclic Loads and High Axial Loads

Buildings, 2023
Experimental observations on three reinforced concrete shear walls with small shear span-to-depth ratio (SDR) under combined high vertical axial load and horizontal cyclic loads are presented.
Chenhua Jin, Yanli Su, Zuanfeng Pan, Shaoping Meng   +3 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source