Dynamic Behavior Analysis on a New Type of Downhole Tractor Stepping Mechanism
Shiyou jixie, 2020 The traditional calculation method for the motion analysis of the ball screw pair of the downhole tractor stepping mechanism does not consider the inertial load of the rolling element. The vector analysis method is used to perform a kinematic analysis on
Li Xiangyu +4 more
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Mechanical behavior analysis of fully grouted bolt under axial load. [PDF]
Sci Rep, 2023 Liu X, Ma Z.
europepmc +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Mechanical Properties of Full-Scale UHPC-Filled Steel Tube Composite Columns under Axial Load. [PDF]
Materials (Basel), 2023 Cheng B +5 more
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Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
A Numerical and Experimental Analysis of the Mechanical Behavior of the Aluminum Beverage Can with Internal Varnish Layers during Axial Load Force Testing. [PDF]
Materials (Basel), 2023 Wędrychowicz P, Kustra P, Milenin A.
europepmc +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Prediction of Stress-Strain Curves for HFRP Composite Confined Brick Aggregate Concrete under Axial Load. [PDF]
Polymers (Basel), 2023 Saingam P +6 more
europepmc +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Pump Indicator Diagram Simulation Model based on Measured Axial Load of Tubing Head
Shiyou jixie, 2016 Pump diagnosis technique of rod pumped well is to convert polished rod indicator diagram into pump indicator diagram by using wave equation for longitudinal vibration of sucker rod string on the basis of measured polished rod indicator diagram.
Yao Chundong +4 more
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