Results 81 to 90 of about 75,134 (266)

Experimental Study on the Seismic Performance of Pre-Inserted Prefabricated Shear Walls

open access: yesBuildings
The pre-inserted method for precast shear walls involves casting concealed beams at floor slabs between upper and lower structures, with precast concrete supports spaced at intervals.
Quanbiao Xu   +4 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

open access: yesFEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso   +4 more
wiley   +1 more source

Comportamiento experimental de uniones interiores viga plana-columna de concreto armado bajo acciones sísmicas y carga axial Experimental behaviour of RC interior wide beam-column joint subject seismic actions and axial load

open access: yesRevista Técnica de la Facultad de Ingeniería, 2009
Este trabajo presenta un modelo experimental que muestra la influencia de la carga axial en las juntas interiores viga plana-columna de concreto armado sometida a desplazamientos laterales simulando su comportamiento ante un sismo.
Marcial Hurtado-Alvarado   +1 more
doaj  

Study on dynamics characteristics and energy dissipation laws of coal fracture under low−speed impact load

open access: yesMeitan kexue jishu
To explore the dynamic characteristics and energy dissipation laws of coal fracture instability under varied impact loads, using an improved Hopkinson bar (SHPB) test system was used to conduct one-dimensional impact load, impact load and axial static ...
Di HE   +6 more
doaj   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

open access: yesFEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl   +13 more
wiley   +1 more source

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