Results 41 to 50 of about 1,606,706 (292)

Multi-parameter analysis of the effects on hydraulic performance and hemolysis of blood pump splitter blades

open access: yesAdvances in Mechanical Engineering, 2020
The splitter blade can effectively optimize pump performance, but there is still insufficient research in blood pumps that cover both hydraulic and hemolysis performance. Thus, the aim of this study was to investigate the effect of key factors related to
Zheqin Yu, Jianping Tan, Shuai Wang
doaj   +1 more source

Axially-offset differential interference contrast microscopy via polarization wavefront shaping

open access: yesOptics Express, 2019
Sample-scan phase contrast imaging was demonstrated by producing and coherently recombining light from a pair of axially offset focal planes. Placing a homogeneous medium in one of the two focal planes enables quantitative phase imaging using only common-path optics, recovering absolute phase without halo or oblique-illumination artifacts.
Changqin, Ding   +3 more
openaire   +2 more sources

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Influence of design parameters on the global performances of low-speed counter-rotating axial-flow fans [PDF]

open access: yes, 2014
The present work aims at experimentally investigating the effects of some parameters on the performances of a counter-rotating stage, and on the instationary flow between the rotors.
BAKIR, Farid   +5 more
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Getting down to business: the producer offset five years on [PDF]

open access: yes, 2012
  The Producer Offset was introduced in July 2007 as part of the Australian Screen Production Incentive (ASPI), the Australian Government\u27s package of measures to boost support for the Australian film and television industry. One of the key aims

core  

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Classical and numerical approaches to determining V-section band clamp axial stiffness [PDF]

open access: yes, 2014
V-band clamp joints are used in a wide range of applications to connect circular flanges, for ducts, pipes and the turbocharger housing. Previous studies and research on V-bands are either purely empirical or analytical with limited applicability on the ...
Khodabakhshi, Goodarz   +6 more
core   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Investigating the Interhemisphere 14C Offset in the 1st Millennium AD and Assessment of Laboratory Bias and Calibration Errors [PDF]

open access: yes, 2009
Past measurements of the radiocarbon interhemispheric offset have been restricted to relatively young samples because of a lack of older dendrochronologically secure Southern Hemisphere tree-ring chronologies. The Southern Hemisphere calibration data set
Palmer, Jonathan G.   +11 more
core   +1 more source

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