Results 211 to 220 of about 45,474,262 (309)

Adjusting for Medication Use in GWAS and Its Impact on Mendelian Randomisation Analyses: An Example of Systolic Blood Pressure in UK Biobank

open access: yesGenetic Epidemiology, Volume 50, Issue 8, December 2026.
ABSTRACT Medication use is common in large‐scale population cohorts, and can modify phenotypic traits of interest. This can potentially bias effect estimates in genome‐wide association studies (GWAS) and impact downstream analyses such as Mendelian randomisation (MR). The best approach to account for medication use in GWAS is unclear. In this study, we
Aaron Jun Yi Yap   +3 more
wiley   +1 more source

New‐Onset Type 2 Diabetes Mellitus and Cancer Risk: A Matched Cohort Study in China Kadoorie Biobank

open access: yesInternational Journal of Cancer, Volume 159, Issue 11, Page 2705-2719, 1 December 2026.
ABSTRACT The prevalence of type 2 diabetes mellitus (T2DM) is rising rapidly in China and is linked to increased cancer risk, but causality remains unclear due to biases. We examined the causal effect of T2DM on cancer risk using bias‐minimizing methods.
Mengying Wang   +9 more
wiley   +1 more source

A Top–Down Thermodynamically Motivated Perspective on Multiscale Material Modeling

open access: yesProceedings in Applied Mathematics and Mechanics, Volume 26, Issue 4, December 2026.
ABSTRACT Established multiscale strategies such as QM/MM coupling, computational homogenization, quasi‐continuum approaches, and thermodynamically formulated continuum models provide powerful scale‐bridging tools, however, each of them is formulated on a different effective energetic level, and an explicit recursive energy reference structure ...
Andreas Warkentin
wiley   +1 more source

Gradient Systems and Scale‐Aware Heat Equations

open access: yesProceedings in Applied Mathematics and Mechanics, Volume 26, Issue 4, December 2026.
ABSTRACT The extreme miniaturization of modern microelectronic architectures exposes the limitations of classical continuum mechanics, as Fourier's law breaks down at sub‐micron scales (100–0.1 μm$\umu{\rm m}$). While molecular models can accurately capture these thermal flow regimes, they remain computationally expensive.
Grigor Nika
wiley   +1 more source

Combining phenomic and genomic selection for pea breeding improvement

open access: yesThe Plant Phenome Journal, Volume 9, Issue 1, December 2026.
Abstract Pea (Pisum sativum L.) is a strategic crop in the development of sustainable agriculture. However, the genetic gain remains limited despite advances in breeding. Genomic selection holds promise to accelerate varietal improvement, but its high implementation cost restricts its use in crops.
Anthony Klein   +15 more
wiley   +1 more source

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