Results 21 to 30 of about 19,273 (245)

Rational Analysis of Melting Point Behavior of Co-Crystals of 4‑Nitrophenol with Some Aza-Compounds

, 2016
Various co-crystals of 4-nitrophenol with aza-compounds have been synthesized and characterized by single-crystal X-ray diffraction method. Thermal analysis of all the co-crystals infers higher melting point compared to their respective co-formers and ...
V. R. Pedireddi (1556773), Amrita Nayak, V. R. Pedireddi, Amrita Nayak (3131595)   +3 more
core   +1 more source

Chlorine-Substituted 9,10-Dihydro-9-aza-10-boraanthracene as a Precursor for Various Boron- and Nitrogen-Containing π‑Conjugated Compounds

, 2019
Chlorine-substituted 9,10-dihydro-9-aza-10-bora­anthracene was synthesized. Derivatization of this compound by taking advantage of the transformable B–Cl moiety gave 9,10-dihydro-9-aza-10-boraanthracene derivatives with various aryl substituents.
Shin-ya Nema (6426149), Makoto Yamashita (216887), Yutaro Ishikawa (6426146), Katsunori Suzuki (458282), Kohei Hayashi (2491297)   +4 more
core   +2 more sources

An efficient one-pot route to an aza-bridged bis-phenanthroline macrocyclic compound

, 2009
A facile synthesis of an aza-bridged bis-1,10-phenanthroline macrocycle is described. X-ray crystallographic analysis of the aza-bridged bis-1,10-phenanthroline revealed that the two central hydrogen atoms were localized on two of the opposite central ...
王文竹; Wang, Wen-jwu; Chuang, Kuo-shen; Luo, Chi-fong; Liu, Hai-yang
core   +1 more source

[18F]Fluorodeprenyl‐D2 PET as a Tool to Monitor Disease Activity in GAD65‐Ab Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate [18F]fluorodeprenyl‐D2 ([18F]F‐DED) positron‐emission tomography (PET) imaging as a biomarker of disease activity in autoimmune encephalitis (AIE) associated with glutamic acid decarboxylase 65 (GAD65) antibodies. Methods [18F]F‐DED PET was performed in 25 GAD65‐AIE patients and 8 controls using dynamic (0–60 min) and ...
Julia S. Dorneich, Jonathan A. Gernert, Hanna Zimmermann, Lisa Tagnin, Marianthi Zeinaki, Laura Sanzo, Letizia Vogler, Elisabeth Kaufmann, Justina Dargvainiene, Frank Leypoldt, Gérard N. Bischof, Robert Perneczky, Boris‐Stephan Rauchmann, Simon Lindner, Günter U. Höglinger, Rudolf A. Werner, Martin Kerschensteiner, Tania Kümpfel, Matthias Brendel, Franziska S. Thaler   +19 more
wiley   +1 more source

Understanding Further the Phenotypic Spectrum of Central Nervous System Inflammatory Demyelinating Disorders Using Unsupervised Clustering

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Central nervous system (CNS) inflammatory demyelinating syndromes, including multiple sclerosis (MS), aquaporin‐4 antibody–positive neuromyelitis optica spectrum disorder (AQP4 + NMOSD), and myelin oligodendrocyte glycoprotein (MOG) antibody–associated disease (MOGAD), occasionally overlap.
Bade Gulec, Elif Everest, Melih Tutuncu, Ugur Bilge, Sabahattin Saip, Ugur Uygunoglu, Aksel Siva   +6 more
wiley   +1 more source

Ofatumumab in Myelin Oligodendrocyte Glycoprotein Antibody–Associated Disease: A Comparison With Rituximab

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan, Lei Zhou, Jingzi ZhangBao, Hongmei Tan, Zhouzhou Wang, Chao Quan   +5 more
wiley   +1 more source

Long‐Term Efficacy of Immunotherapy in Autoimmune Autonomic Ganglionopathy—A 10‐Year Follow Up Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autoimmune autonomic ganglionopathy (AAG) is a rare but potentially treatable cause of severe autonomic failure. Evidence guiding long‐term immunotherapy, treatment sequencing, and residual autonomic impairment is limited. We evaluated long‐term treatment response, residual autonomic dysfunction, and relapse patterns in patients with
Giacomo Chiaro, Shiwen Koay, Gordon T. Ingle, Patricia McNamara, Laura Watson, Fion Bremner, Valeria Iodice   +6 more
wiley   +1 more source

Light‐Actuated Fiber‐Climbing Inchworm Robot Toward Endoluminal Navigation

Advanced Functional Materials, EarlyView.
A kirigami‐inspired soft inchworm robot harnesses optical energy from a customized side‐emitting optical fiber, guaranteeing its propulsion along the fiber body. The wavelength‐selective responsiveness of dye‐functionalized liquid crystal elastomers and the application of temporal illumination patterns enable sequential control of robot components. The
Antonio Lobosco, Leilei Song, Fan Liu, Yu‐Hsiang Lin, Venkatasubramanian Kalpathy Venkiteswaran, Hao Zeng, Sarthak Misra   +6 more
wiley   +1 more source

Catalytic Functionalization of Unactivated π‐Bonds Enabled by Bidentate Directing Auxiliaries

Angewandte Chemie, EarlyView.
This review explores how bidentate directing auxiliaries have advanced transition‐metal catalysis for unactivated alkene/alkyne functionalization. By leveraging chelated intermediates, bidentate directing auxiliaries enable precise hydrofunctionalization, difunctionalization, and C─H activation of π‐bonds with unique selectivity and reactivity.
Seunghyeon Cho, Al Vicente Riano D. Lisboa, Juntao Sun, Taeho Kang, Keary M. Engle   +4 more
wiley   +2 more sources

Nanobody‐Conjugated Theranostic Prodrug Targeting αvβ3 Integrin Enables Precision Cancer Therapy With Real‐Time Imaging

Advanced Healthcare Materials, EarlyView.
The image shows a schematic form a nanobody‐conjugated theranostic prodrug (NBD) platform targeting tumor‐associated αvβ3 integrin. The NBD system integrates selective nanobody‐mediated tumor recognition, glutathione‐responsive disulfide cleavage for doxorubicin release, and aza‐BODIPY‐based near‐infrared fluorescence for real‐time imaging.
Sanu Karan, Hyunseung Lee, Rema Naskar, Mi Young Cho, Hye Sun Park, Eun Hee Han, Soumyadip Hore, Sun Hee Cho, Truc Ngoc Kim Lam, Taewoong Son, Tae Jung Park, Inkyu Hwang, Jonathan L. Sessler, Kwan Soo Hong   +13 more
wiley   +1 more source