Features of clinically significant portal hypertension (CSPH) in patients with autoimmune hepatitis indicate a substantial risk for decompensation and impaired transplant‐free survival. Non‐invasive risk prediction based on liver stiffness measurement ≥ 15 kPa and/or thrombocytopenia (< 150 G/L) serves as a valuable surrogate to identify patients at ...
Lukas Burghart+10 more
wiley +1 more source
Comparison of endoscopic healing and durability between combination therapy with infliximab and azathioprine versus infliximab monotherapy in pediatric Crohn's disease. [PDF]
Kim YZ+6 more
europepmc +1 more source
Key aspects of this survey focused on treatment approach, controlling immune thrombocytopenia (ITP), health‐related quality of life (HRQOL) and patient support. Although most patients were receiving and adhering to ITP treatment, there was a lack of sustained efficacy, fuelling a need for better and more effective treatment options.
Nichola Cooper+10 more
wiley +1 more source
Penile erosions: an atypical initial manifestation of pemphigus vulgaris. [PDF]
Leme HJ+4 more
europepmc +1 more source
Predictors of response to emergent therapies in paediatric immune thrombocytopenia
Emergent therapies (ET), which include intravenous immunoglobulin (IVIG), corticosteroids and intravenous anti‐Rho(D) immunoglobulin, are used to treat acute episodes of bleeding in children with immune thrombocytopenia (ITP). Through comparison of clinical characteristics in paediatric patients with ITP responsive to ET versus those non‐responsive to ...
Candelaria O'Farrell+7 more
wiley +1 more source
Treatment options for immune‐related adverse events associated with immune checkpoint inhibitors
Abstract The immunotherapy revolution with the use of immune checkpoint inhibitors (ICIs) started with the clinical use of the first ICI, ipilimumab, in 2011. Since then, the field of ICI therapy has rapidly expanded — with the FDA approval of 10 different ICI drugs so far and their incorporation into the therapeutic regimens of a range of malignancies.
Yu Hua Chen+3 more
wiley +1 more source
Titanium: An Unusual Allergen With Various Presentations—A Retrospective Cohort Study
Titanium, a rare allergen, should be tested in the suitable clinical setting, taking into consideration the anticipated rise in exposure through medical equipment, implants and recreational ‘Nickel free’ jewellery and tattoos. Titanium induced BP is an intriguing phenomenon that should be further explored, on the verge between allergology and ...
Danny Daniely+4 more
wiley +1 more source
Myelodysplastic Syndrome in a Patient With Cronkhite-Canada Syndrome. [PDF]
Shim KG+4 more
europepmc +1 more source
Summary Background and Objectives Systemic treatment of pregnant/breastfeeding atopic dermatitis (AD) patients is challenging due to limited safety data. We explored treatment practices with systemic agents, including the guideline‐recommended cyclosporine as the first systemic choice as well as emerging therapies, in this vulnerable population ...
Manuel P. Pereira+34 more
wiley +1 more source
Correlation of Antimuscarinic Acetylcholine Receptor Antibody Titers With Pemphigus Disease Activity at Baseline and Following Phase I Pulse Therapy. [PDF]
Behera B+4 more
europepmc +1 more source