Results 311 to 320 of about 129,283 (392)

Are single nucleotide polymorphisms underutilized for guiding treatment of inflammatory bowel disease?

open access: yesImmunology &Cell Biology, EarlyView.
Patients with inflammatory bowel disease (IBD) show variation in their response to therapeutics. This review explores the contrast between heritable single nucleotide polymorphisms (SNPs) that contribute the pathogenesis of IBD, versus those that associate with response to treatments.
Jildou van der Werf   +1 more
wiley   +1 more source

Connective tissue disease‐associated interstitial lung disease: an approach to treatment amidst an expanding evidence base

open access: yesInternal Medicine Journal, EarlyView.
ABSTRACT Connective tissue disease‐associated interstitial lung disease (CTD‐ILD) comprises a heterogenous group of conditions characterised by immune‐mediated fibro‐inflammatory pulmonary injury. Although the disease course is variable, CTD‐ILD can progress to respiratory failure and thus has a profound impact on morbidity and mortality.
Michael Hong   +2 more
wiley   +1 more source

European Guideline (EuroGuiDerm) on atopic eczema: Living update

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
The updated guideline includes a new evidence‐based recommendation for the IL‐13 inhibitor lebrikizumab. In addition, the Janus kinase inhibitors baricitinib and abrocitinib, which were initially only approved for adult patients, are now also recommended for children from the age of 2 and adolescents from the age of 12, respectively.
A. Wollenberg   +31 more
wiley   +1 more source

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