Results 31 to 40 of about 23,651 (105)
Adapted Treatment Guided by Interim PET-CT Scan in Advanced Hodgkin’s Lymphoma
New England Journal of Medicine, 2016 Background We tested interim positron-emission tomography–computed tomography (PET-CT) as a measure of early response to chemotherapy in order to guide treatment for patients with advanced Hodgkin’s lymphoma.P. Johnson, M. Federico, A. Kirkwood, A. Fosså, L. Berkahn, A. Carella, F. d'Amore, G. Enblad, A. Franceschetto, M. Fulham, S. Luminari, M. O'Doherty, P. Patrick, T. Roberts, Gamal Sidra, L. Stevens, Paul D. Smith, J. Trotman, Z. Viney, J. Radford, S. Barrington +20 moresemanticscholar +1 more sourceThe grapevine genome sequence suggests ancestral hexaploidization in major angiosperm phyla
Nature, 2007 The analysis of the first plant genomes provided unexpected evidence for genome duplication events in species that had previously been considered as true diploids on the basis of their genetics.O. Jaillon, J. Aury, B. Noel, A. Policriti, C. Clépet, A. Casagrande, N. Choisne, S. Aubourg, N. Vitulo, Claire Jubin, A. Vezzi, F. Legeai, P. Hugueney, C. Dasilva, D. Horner, E. Mica, D. Jublot, J. Poulain, Clémence Bruyère, A. Billault, Béatrice Segurens, M. Gouyvenoux, Edgardo Ugarte, F. Cattonaro, Véronique Anthouard, V. Vico, C. D. Fabbro, M. Alaux, G. Gaspero, V. Dumas, Nicoletta Felice, S. Paillard, Irena Juman, M. Moroldo, S. Scalabrin, Aurélie Canaguier, I. Clainche, G. Malacrida, E. Durand, G. Pesole, V. Laucou, P. Chatelet, Didier Merdinoglu, Massimo Delledonne, M. Pezzotti, A. Lecharny, Claude Scarpelli, F. Artiguenave, M. Pè, G. Valle, Michele Morgante, Michel Caboche, A. Adam-Blondon, J. Weissenbach, F. Quétier, P. Wincker +55 moresemanticscholar +1 more sourceDiscovery and refinement of loci associated with lipid levels
Nature Genetics, 2013 Levels of low-density lipoprotein (LDL) cholesterol, high-density lipoprotein (HDL) cholesterol, triglycerides and total cholesterol are heritable, modifiable risk factors for coronary artery disease.Cristen J Ellen M Sebanti Gina M Stefan Stavroula Andrea J Willer Schmidt Sengupta Peloso Gustafsson Kanoni G, C. Willer, Ellen M. Schmidt, Sebanti Sengupta, G. Peloso, S. Gustafsson, S. Kanoni, A. Ganna, Jin Chen, Martin L. Buchkovich, S. Mora, J. Beckmann, J. Bragg-Gresham, Hsing-Yi Chang, A. Demirkan, H. D. den Hertog, R. Do, L. Donnelly, G. Ehret, T. Esko, M. Feitosa, T. Ferreira, K. Fischer, P. Fontanillas, Ross M. Fraser, D. Freitag, D. Gurdasani, K. Heikkilä, E. Hyppönen, A. Isaacs, A. Jackson, Å. Johansson, T. Johnson, M. Kaakinen, J. Kettunen, M. Kleber, Xiaohui Li, J. Luan, L. Lyytikäinen, P. Magnusson, M. Mangino, E. Mihailov, M. Montasser, M. Müller-Nurasyid, I. Nolte, J. O’Connell, Cameron Palmer, M. Perola, A. Petersen, S. Sanna, R. Saxena, S. Service, Sonia H. Shah, D. Shungin, C. Sidore, Ci Song, R. Strawbridge, I. Surakka, Toshiko Tanaka, T. Teslovich, G. Thorleifsson, E. G. van den Herik, B. Voight, K. Volcik, L. Waite, A. Wong, Ying Wu, Weihua Zhang, D. Absher, G. Asiki, I. Barroso, L. Been, J. Bolton, L. Bonnycastle, P. Brambilla, M. Burnett, G. Cesana, M. Dimitriou, A. Doney, A. Döring, P. Elliott, S. Epstein, G. Eyjolfsson, B. Gigante, M. Goodarzi, H. Grallert, Martha L. Gravito, C. Groves, G. Hallmans, A. Hartikainen, C. Hayward, D. Hernandez, A. Hicks, H. Hólm, Y. Hung, T. Illig, Michelle R Jones, P. Kaleebu, J. Kastelein, K. Khaw, Eric Kim, N. Klopp, P. Komulainen, M. Kumari, C. Langenberg, T. Lehtimäki, Shih-Yi Lin, J. Lindström, R. Loos, F. Mach, W. McArdle, C. Meisinger, B. Mitchell, Gabrielle Müller, R. Nagaraja, Narisu Narisu, T. Nieminen, R. Nsubuga, I. Olafsson, K. Ong, A. Palotie, Theodore Papamarkou, C. Pomilla, A. Pouta, D. Rader, M. Reilly, P. Ridker, F. Rivadeneira, I. Rudan, A. Ruokonen, N. Samani, H. Scharnagl, J. Seeley, K. Silander, A. Stančáková, K. Stirrups, A. Swift, L. Tiret, A. Uitterlinden, L. V. Van Pelt, S. Vedantam, N. Wainwright, C. Wijmenga, S. Wild, G. Willemsen, T. Wilsgaard, James F. Wilson, E. Young, J. Zhao, L. Adair, D. Arveiler, T. Assimes, S. Bandinelli, F. Bennett, M. Bochud, B. Boehm, D. Boomsma, I. Borecki, S. Bornstein, P. Bovet, M. Burnier, H. Campbell, A. Chakravarti, J. Chambers, Y. Chen, F. Collins, Richard S. Cooper, J. Danesh, G. Dedoussis, U. de Faire, Alan B. Feranil, J. Ferrières, L. Ferrucci, N. Freimer, C. Gieger, L. Groop, V. Gudnason, U. Gyllensten, A. Hamsten, T. Harris, A. Hingorani, J. Hirschhorn, A. Hofman, G. K. Hovingh, C. Hsiung, S. Humphries, S. Hunt, K. Hveem, C. Iribarren, M. Järvelin, A. Jula, M. Kähönen, J. Kaprio, Antero Y. Kesäniemi, M. Kivimaki, J. Kooner, P. Koudstaal, R. Krauss, D. Kuh, J. Kuusisto, K. Kyvik, M. Laakso, T. Lakka, L. Lind, C. Lindgren, N. Martin, W. März, M. McCarthy, C. McKenzie, P. Meneton, A. Metspalu, L. Moilanen, A. Morris, P. Munroe, I. Njølstad, N. Pedersen, C. Power, P. Pramstaller, J. Price, B. Psaty, T. Quertermous, R. Rauramaa, D. Saleheen, V. Salomaa, D. Sanghera, Jouko Saramies, P. Schwarz, W. Sheu, A. Shuldiner, A. Siegbahn, T. Spector, K. Stefánsson, D. Strachan, B. Tayo, E. Tremoli, J. Tuomilehto, M. Uusitupa, C. V. van Duijn, P. Vollenweider, L. Wallentin, N. Wareham, J. Whitfield, B. Wolffenbuttel, J. Ordovás, E. Boerwinkle, Colin N. A. Palmer, U. Thorsteinsdóttir, D. Chasman, J. Rotter, P. Franks, S. Ripatti, L. Cupples, M. Sandhu, S. Rich, M. Boehnke, P. Deloukas, S. Kathiresan, K. Mohlke, E. Ingelsson, G. Abecasis +259 moresemanticscholar +1 more sourceThe genome of the domesticated apple (Malus × domestica Borkh.)
Nature Genetics, 2010 We report a high-quality draft genome sequence of the domesticated apple (Malus × domestica). We show that a relatively recent (>50 million years ago) genome-wide duplication (GWD) has resulted in the transition from nine ancestral chromosomes to 17 ...R. Velasco, A. Zharkikh, J. Affourtit, A. Dhingra, A. Cestaro, A. Kalyanaraman, P. Fontana, Satish K. Bhatnagar, M. Troggio, D. Pruss, S. Salvi, M. Pindo, P. Baldi, S. Castelletti, Marina Cavaiuolo, G. Coppola, F. Costa, V. Cova, A. D. Ri, V. Goremykin, M. Komjanc, S. Longhi, P. Magnago, G. Malacarne, M. Malnoy, D. Micheletti, M. Moretto, M. Perazzolli, A. Si-Ammour, S. Vezzulli, E. Zini, G. Eldredge, Lisa M. Fitzgerald, N. Gutin, J. Lanchbury, T. Macalma, Jeff T Mitchell, J. Reid, B. Wardell, C. Kodira, Zhoutao Chen, Brian A. Desany, Faheem Niazi, M. Palmer, Tyson Koepke, D. Jiwan, S. Schaeffer, V. Krishnan, Changjun Wu, Vu T Chu, S. T. King, Jessica L. Vick, Q. Tao, A. Mraz, A. Stormo, K. Stormo, R. Bogden, D. Ederle, A. Stella, Alberto Vecchietti, M. Kater, S. Masiero, P. Lasserre, Y. Lespinasse, A. Allan, V. Bus, D. Chagné, R. Crowhurst, A. Gleave, E. Lavezzo, Jeffrey A. Fawcett, S. Proost, P. Rouzé, L. Sterck, S. Toppo, B. Lazzari, R. Hellens, C. Durel, A. Gutin, Roger E Bumgarner, S. Gardiner, M. Skolnick, M. Egholm, Y. Peer, F. Salamini, R. Viola +85 moresemanticscholar +1 more sourceGenomewide Association Analysis of Coronary Artery Disease
New England Journal of Medicine, 2007 BACKGROUND Modern genotyping platforms permit a systematic search for inherited components of complex diseases. We performed a joint analysis of two genomewide association studies of coronary artery disease.N. Samani, J. Erdmann, A. Hall, C. Hengstenberg, M. Mangino, Bjoern Mayer, R. Dixon, T. Meitinger, P. Braund, H. Wichmann, J. Barrett, I. König, Suzanne E Stevens, S. Szymczak, D. Tregouet, M. Iles, F. Pahlke, Helen Pollard, W. Lieb, F. Cambien, M. Fischer, W. Ouwehand, S. Blankenberg, A. Balmforth, A. Baessler, S. Ball, T. Strom, Ingrid Brænne, C. Gieger, P. Deloukas, M. Tobin, A. Ziegler, J. Thompson, H. Schunkert +33 moresemanticscholar +1 more sourceMEF promotes stemness in the pathogenesis of gliomas
Cell Stem Cell, 2012 Summary High-grade gliomas are aggressive and uniformly fatal tumors, composed of a heterogeneous population of cells that include many with stem cell-like properties.E. Bazzoli, T. Pulvirenti, Moritz C. Oberstadt, F. Perna, Boyoung Wee, N. Schultz, Jason T. Huse, Elena I. Fomchenko, Francesca Voza, Viviane Tabar, Cameron W. Brennan, L. DeAngelis, Stephen D. Nimer, Eric C. Holland, M. Squatrito +14 moresemanticscholar +1 more sourceCommon genetic determinants of vitamin D insufficiency: a genome-wide association study
The Lancet, 2010 Background Vitamin D is crucial for maintaining musculoskeletal health. Recently, vitamin D insufficiency has been linked to a number of extraskeletal disorders, including diabetes, cancer, and cardiovascular disease.Thomas J. Wang, Feng Zhang, J. B. Richards, B. Kestenbaum, J. V. van Meurs, D. Berry, Douglas P. Kiel, E. Streeten, C. Ohlsson, Daniel L. Koller, L. Palotie, Jason D. Cooper, Paul F. O’Reilly, Denise K. Houston, Nicole L. Glazer, L. Vandenput, M. Peacock, J. Shi, F. Rivadeneira, M. McCarthy, Pouta Anneli, I. D. de Boer, M. Mangino, B. Kato, D. Smyth, Sarah L. Booth, P. F. Jacques, Greg L. Burke, M. Goodarzi, C. Cheung, M. Wolf, K. Rice, D. Goltzman, N. Hidiroglou, M. Ladouceur, S. Hui, N. Wareham, L. Hocking, D. Hart, N. Arden, Cyrus Cooper, S. Malik, William D. Fraser, A. Hartikainen, G. Zhai, Helen M. Macdonald, N. Forouhi, Ruth J. F. Loos, David M. Reid, Alan J Hakim, E. Dennison, Yongmei Liu, C. Power, H. Stevens, Laitinen Jaana, R. Vasan, N. Soranzo, J. Bojunga, Bruce M. Psaty, M. Lorentzon, T. Foroud, Tamara B. Harris, A. Hofman, John-Olov Jansson, Jane A Cauley, A. Uitterlinden, Q. Gibson, M. Järvelin, D. Karasik, D. Siscovick, M. Econs, S. Kritchevsky, Jose C. Florez, John A. Todd, J. Dupuis, E. Hypponen, T. Spector +76 moresemanticscholar +1 more sourceFrequency of the C9ORF72 hexanucleotide repeat expansion in ALS and FTD in diverse populations: a cross-sectional study
Lancet Neurology, 2012 Background A hexanucleotide repeat expansion in the C9ORF72 gene has recently been shown to cause a large proportion of amyotrophic lateral sclerosis (ALS) and fronto-temporal dementia (FTD).E. Majounie, A. Renton, K. Mok, E. Dopper, A. Waite, S. Rollinson, A. Chiò, G. Restagno, N. Nicolaou, J. Simón-Sánchez, J. V. van Swieten, Yevgeniya A. Abramzon, Janel O. Johnson, M. Sendtner, R. Pamphlett, R. Orrell, S. Mead, K. Sidle, H. Houlden, J. Rohrer, K. Morrison, H. Pall, Kevin Talbot, O. Ansorge, D. Hernandez, S. Arepalli, M. Sabatelli, G. Mora, M. Corbo, F. Giannini, A. Calvo, Elisabet Englund, G. Borghero, G. Floris, A. Remes, Hannu Laaksovirta, L. McCluskey, J. Trojanowski, V. V. Van Deerlin, G. Schellenberg, M. Nalls, V. Drory, C. Lu, T. Yeh, H. Ishiura, Yuji Takahashi, S. Tsuji, I. Le Ber, Alexis Brice, C. Drepper, Nigel M. Williams, J. Kirby, Pamela J. Shaw, John A Hardy, P. Tienari, P. Heutink, H. Morris, S. Pickering-Brown, B. Traynor +58 moresemanticscholar +1 more sourceKiri Vittorio Emmanuele Azegliole [PDF]
Azeglio, Massimo Taparelli d', 1798-1866, itaalia kirjanik ja poliitik, markiiAzeglio, Vittorio Emmanuele Taparelli d`, 1815/16-1890, itaalia diplomaatKahetseb, et ei saa tulla Milanosse adressaadiga ...D'Azeglio, Massimocore