Results 211 to 220 of about 71,483 (285)

Evaluation of Drug–Drug Interaction Potential Between the Oral Antibiotic Zoliflodacin and the CYP3A4 Inhibitor Itraconazole: A Phase 1 Study in Healthy Participants

Clinical and Translational Science, Volume 19, Issue 3, March 2026.
ABSTRACT Zoliflodacin is a first‐in‐class oral spiropyrimidinetrione antibiotic being developed for patients with uncomplicated gonorrhea, including those infected with multidrug‐resistant strains. Because zoliflodacin is metabolized by cytochrome P450 3A4 (CYP3A4), concomitant administration with a CYP3A inhibitor has the potential to increase ...
Alison Luckey, Kajal B. Larson, Noha Rayad, Markus Heep, Sophie Delhomme, Gabrielle Kornmann, John P. Mueller, John P. O'Donnell, Seamus O'Brien, Rainard Fuhr, Jean‐Yves Gillon   +10 more
wiley   +1 more source

Efficacy of Azithromycin 1% in the Clinical Management of Bacterial Conjunctivitis.

J Pharm Bioallied Sci
Suthar AH.
europepmc   +1 more source

Comparative Impacts of Oral Amoxicillin, Azithromycin, and Clindamycin on Gut Microbiota and Intestinal Homeostasis. [PDF]

Antibiotics (Basel)
Li S, Sun J, Ren Y, Wang S.
europepmc   +1 more source

A retrospective case series of 66 foals with presumed acute interstitial pneumonia

Equine Veterinary Education, Volume 38, Issue 3, Page 143-153, March 2026.
Summary Background There is limited literature describing acute interstitial pneumonia (AIP) in foals. Objectives Description of clinical and ultrasonographic findings in 66 foals affected by AIP. Investigation into whether the number of AIP cases is associated with specific climatic conditions. We also investigated whether clinical, haematological and
L. Weißlein, F. Freise, M. Venner
wiley   +1 more source

Simulating treatment effects for gonorrhoea using a within-host mathematical model. [PDF]

Infect Dis Model
Jayasundara P, Regan DG, Kuchel P, Wood JG.   +3 more
europepmc   +1 more source

The potential value of cytokine, cortisol and vitamin D profiles in foals from birth to weaning for respiratory disease prediction on a farm endemic for Rhodococcus equi pneumonia

Equine Veterinary Journal, Volume 58, Issue 2, Page 359-371, March 2026.
Abstract Background Rhodococcus equi causes pneumonia in young foals, but disease susceptibility and severity vary. Cortisol and vitamin D modulate immune responses and cytokine production during bacterial infection, and altered concentrations are associated with sepsis in neonatal foals. We hypothesised an age and disease effect on circulating steroid
Londa J. Berghaus, Monica Venner, Hannah Helbig, Dorothea Hildebrandt, Kelsey Hart   +4 more
wiley   +1 more source

Prophylactic antibiotics to prevent chest infections in children with neurological impairment: the PARROT RCT.

Health Technol Assess
McNamara PS, Jones AP, Chang A, Crabtree K, Crompton K, Dehghani S, Eccleson H, Fothergill J, Grigg J, Gringras P, Harvey A, Heys M, Hughes DA, McCallum G, McLennan K, Morris C, Nuttall A, Parr J, Perez YP, Reddihough D, Semple MG, Smallman H, Wan M, Williams K.   +23 more
europepmc   +1 more source

Antibacterial potential of danthron, embelin, sanguinarine and shikonin against multidrug-resistant Neisseria gonorrhoeae in vitro. [PDF]

Int Microbiol
Qi Y, Zhang R, Peng H, Tao C, Tang Y, Lu S, Ke Q, Shen S, Wang Z, Lin X.   +9 more
europepmc   +1 more source

Late diagnosis of paediatric HIV infection in high‐income countries: Lessons from the HIV Perinatal Virtual Clinic

HIV Medicine, Volume 27, Issue 3, Page 477-484, March 2026.
Abstract Introduction Timely diagnosis of HIV in children remains a challenge in all settings including low‐prevalence, high‐income countries (HIC). We aimed to characterize the prevalence of late diagnosis, and prior missed diagnostic opportunities among new presentations of paediatric HIV in HIC referred to an international Perinatal Virtual Clinic ...
Carolina Curto, M. Tritzali, A. Bamford, A. C. Bailey, E. G. H. Lyall, N. E. Mackie, N. Tickner, C. Foster, on behalf of the PVC   +8 more
wiley   +1 more source