Results 151 to 160 of about 660 (230)

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

The Protective Effect of Carvacrol Against Isoproterenol-Induced Cardiotoxicity in Rats. [PDF]

Medeni Med J
Ayık S, Erfirat HD, Ozhan O, Gunata M, Yildiz A, Durhan M, Cigremis Y, Parlakpinar H.   +7 more
europepmc   +1 more source

Measure for degree heterogeneity in complex networks and its application to recurrence network analysis. [PDF]

R Soc Open Sci, 2017
Jacob R, Harikrishnan KP, Misra R, Ambika G.   +3 more
europepmc   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Prospects of training system and deficit irrigation for increasing yield and water use efficiency of pitaya (Hylocereus spp.) in the Mediterranean region. [PDF]

BMC Plant Biol
Kaman H, Gübbük H, Altinkaya L, Balkiç R, Ünlü M.   +4 more
europepmc   +1 more source

Investigating the anti-tumoral effect of curcumin on the mice in which Ehrlich ascites and solid tumor is created. [PDF]

Iran J Basic Med Sci, 2019
Yılmaz S, Ülger H, Ertekin T, Yay AH, Nisari M, Alpa Ş, Acer N.   +6 more
europepmc   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Pre-pandemic Autonomic Nervous System Activity Predicts Well-being during COVID-19 in Israel

, 2020
Gordon I, Horesh D, Tomashin A, Milstein N, Mayo O, Korisky A.   +5 more
europepmc   +1 more source

Differential outcomes of venous and arterial tissue engineered vascular grafts highlight the importance of coupling long-term implantation studies with computational modeling. [PDF]

Acta Biomater, 2019
Best CA, Szafron JM, Rocco KA, Zbinden J, Dean EW, Maxfield MW, Kurobe H, Tara S, Bagi PS, Udelsman BV, Udelsman BV, Khosravi R, Yi T, Shinoka T, Humphrey JD, Breuer CK.   +15 more
europepmc   +1 more source