Results 121 to 130 of about 12,336,620 (246)
Subcellular localization of HS1 in normal and CLL B cells.
(A) Analysis by differential ultracentrifugation. B cells were sonicated in isotonic buffer and nuclei (I), cytosol (II) and microsomes (III) were separated by ultracentrifugation.
Anna Cabrelle (8735) +13 more
core +1 more source
Abstract Traditional item response theory (IRT) models involve symmetric response probability functions, but a developing area of research has focused on asymmetric alternatives. To date, these studies have focused primarily on introducing new asymmetric models, detailing their mathematical formulations, explaining how to interpret their item ...
Hyejin Shim, Wes Bonifay
wiley +1 more source
Thermodynamic characterisation of covalent ligand binding
Background and Purpose Differential scanning fluorimetry (DSF) is a common and straightforward method to evaluate the thermal stability of proteins and has been heavily used for ligand binding characterisation as well as for screening. One class of compounds that is less typically evaluated by DSF are covalent binders.
Rebecca Hertzman +4 more
wiley +1 more source
Bruton tyrosine kinase inhibitors and cardiovascular adverse events
Abstract Bruton tyrosine kinase inhibitors (BTKi) have transformed the management of chronic lymphocytic leukaemia and other B‐cell malignancies, yet their therapeutic benefit is tempered by clinically relevant cardiovascular toxicities (predominantly atrial fibrillation, hypertension, bleeding and ventricular arrhythmias).
Massimiliano Camilli +4 more
wiley +1 more source
VividHairEdit is an advanced StyleGAN2 inversion system for high‐fidelity hair transfer and editing. Our system features improved structural integration, vibrant appearance representation, and optimized latent code selection, achieving superior generation quality and usability. A user‐friendly sketch interface enables precise modifications that reflect
Eunyeong Choi, Sihun Jin, Dongjoon Kim
wiley +1 more source
Progressively Projected Newton's Method
Abstract Newton's Method is widely used to find the solution of complex non‐linear simulation problems. To guarantee a descent direction, it is common practice to clamp the negative eigenvalues of each element Hessian prior to assembly—a strategy known as Projected Newton (PN)—but this perturbation often hinders convergence.
J. A. Fernández‐Fernández +2 more
wiley +1 more source
Rituximab mechanisms of action in B-CLL: a new piece of the puzzle. [PDF]
Watier H.
europepmc +1 more source
Pirtobrutinib in Richter syndrome: Outcomes from the named patient programme in Italy
British Journal of Haematology, EarlyView.
Isacco Ferrarini +19 more
wiley +1 more source
ABSTRACT Squamoid Eccrine Ductal Carcinoma (SEDC) is a rare cutaneous adenexal carcinoma first described in 1997. It has distinct biphasic features on histology which commonly result in misdiagnosis as Bowen disease or cutaneous squamous cell carcinomas (cSCC) if diagnostic skin biopsies are too superficial. This may lead to a delay in diagnosis. It is
Xiang Li Tan +15 more
wiley +1 more source

