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Prognostic B-cell epitopes on the flagellar protein of Borrelia burgdorferi

Infection and Immunity, 1992
Overlapping decapeptides based on the flagellin sequence of Borrelia burgdorferi B31 (G. S. Gassmann, M. Kramer, U. B. Göbel, and R. Wallich, Nucleic Acids Res. 17:3590, 1989) were used to identify immunologically reactive regions of flagellin. Five serum specimens from patients with late manifestations of Lyme disease and borrelia-specific monoclonal ...
T, Schneider   +4 more
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Modulation of Cytokine Signaling by B. burgdorferi

2012
Lyme disease, caused by the spirochete Borrelia burgdorferi sensu lato, is a multisystem disease and the most prevalent tick-borne disease world-wide. The spirochete infects humans and other mammals via the bite of infected Ixodes ticks (Burgdorfer et al. 1982).
Vida A. Dennis   +2 more
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Active immunization with pC protein ofBorrelia burgdorferi protects gerbils againstB. burgdorferi infection

Infection, 1992
Serious infection due to Borrelia burgdorferi and the disseminated infection characteristic of the disease possess unique treatment problems. The wide and still increasing incidence of Lyme borreliosis as well as the problems in treatment call for effective prevention strategies by active immunization.
V, Preac-Mursic   +9 more
openaire   +2 more sources

Surface receptors of neutrophils towards B. burgdorferi.

Wiener klinische Wochenschrift, 1999
The spirochetal agent of Lyme borreliosis, Borrelia burgdorferi, is able to induce an infection which develops in three stages: an early, localized infection, disseminated infection and a third stage, chronic infection, which probably indicates that a protected niche has been established in one or more tissues, where the spirochetes persist even if a ...
M, Cinco   +3 more
openaire   +1 more source

The distribution and prevalence of B. burgdorferi genomospecies in Ixodes ricinus ticks in Ireland

European Journal of Epidemiology, 1997
Questing Ixodes ricinus ticks were collected from six locations throughout Ireland and 638 nymphs, 111 females and 118 males were investigated for infection with Borrelia burgdorferi sensulato (s.l.). The total prevalence of B. burgdorferi s.l. in the ticks was determined as 14.9% by polymerase chain reaction (PCR) amplification of the spacer region of
F, Kirstein   +3 more
openaire   +2 more sources

PREDOMINANCE OF BORRELIA BURGDORFERI SPECIFIC B CELLS IN CEREBROSPINAL FLUID IN NEUROBORRELIOSIS

The Lancet, 1989
A nitrocellulose immunospot assay that allows the counting of cells secreting IgG, IgA, or IgM antibodies to Borrelia burgdorferi was used to compare B cell response to B burgdorferi at the cellular level in cerebrospinal fluid (CSF) and blood from patients with neuroborreliosis with that in patients with aseptic meningoencephalitis (AM) or non ...
S, Baig, T, Olsson, H, Link
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Prevalence of taste disorders in idiopathic and B. burgdorferi-associated facial palsy

Journal of Neurology, 2009
The frequency of taste disorders in idiopathic facial palsy (IFP) and B. burgdorferi-associated facial palsy (BFP) was retrospectively assessed in a cohort of patients with acute peripheral facial palsy (AFP). A significant (>10/microl) CSF pleocytosis was found in 17% of the patients who underwent lumbar puncture for AFP.
Hufschmidt, Andreas   +4 more
openaire   +3 more sources

Comparison of Borrelia burgdorferi ultrasonicate and whole B. burgdorferi cells as a stimulus for T-Cell proliferation and GM-CSF secretion in vitro

Zentralblatt für Bakteriologie, 1993
Peripheral blood mononuclear cells (PBMC) from five patients with confirmed Lyme borreliosis (LB) and from seven seronegative healthy subjects were incubated with ultrasonicated sterile-filtrated B. burgdorferi and with whole live Borrelia burgdorferi cells (strain RT1). PBMC culture conditions were 1 x 10(5) PBMC/well/ 10% autologous plasma (AP) and 2
C, Schempp   +3 more
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A CASE OF DELAYED DIAGNOSIS OF SEVERE B. BURGDORFERI MENINGO-ENCEPHALITIS

Journal of Neurology, Neurosurgery & Psychiatry, 2012
An early diagnosis of neuroborreliosis is imperative, as full recovery may not be achieved with delayed treatment. The diagnosis may be delayed due to atypical presentation of this rare condition. We report a case of 44-year-old farmer with a delayed diagnosis of a severe meningo-myelitis secondary to B.burgdorferi infection.
B Cheripelli, GL Hall
openaire   +1 more source

Three species of Borrelia burgdorferi sensu lato (B. burgdorferi sensu stricto, B afzelii, and B. garinii) identified from cerebrospinal fluid isolates by pulsed-field gel electrophoresis and PCR

Journal of Clinical Microbiology, 1996
A total of 36 European Borrelia burgdorferi sensu lato cerebrospinal fluid isolates (mainly from southern Germany) were analyzed by pulsed-field gel electrophoresis (PFGE) for large restriction fragment pattern (LRFP) and linear plasmid profiles. Analyzing this large panel of isolates, we detected all three species of B.
U, Busch   +6 more
openaire   +2 more sources

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