Management of an outbreak of brucellosis due to B. melitensis in dairy cattle in Spain
Brucella melitensis is a major human and animal pathogen, with a wide host range that includes all domestic ruminant species, although small ruminants are its preferred hosts. Outbreaks in cattle due to B. melitensis have become a worldwide emerging problem particularly difficult to control due to the lack of knowledge on the epidemiology in this host ...
Álvarez Sánchez, Julio +11 more
openaire +4 more sources
Bacteriological and molecular characterization of <i>B. melitensis</i> isolated from aborted sheep and Malta fever patients. [PDF]
Background: Zoonotic diseases pose a major global health concern, particularly those with high prevalence or widespread impact. Brucella melitensis, the causative agent of human brucellosis or undulant fever, is a highly virulent pathogen transmitted mainly through contact with infected animals or consumption of unpasteurized dairy products.
Klaif SF +3 more
europepmc +5 more sources
Antigenic, Immunologic and Genetic Characterization of Rough Strains B.abortus RB51, B.melitensis B115 and B.melitensis B18 [PDF]
The lipopolysaccharide (LPS) is considered the major virulent factor in Brucella spp. Several genes have been identified involved in the synthesis of the three LPS components: lipid A, core and O-PS. Usually, Brucella strains devoid of O-PS (rough mutants) are less virulent than the wild type and do not induce undesirable interfering antibodies.
Rosanna Adone +4 more
openaire +5 more sources
The infection with Brucella abortus, Brucella melitensis and Brucella suis has been assessed according to the criteria of the Animal Health Law (AHL), in particular criteria of Article 7 on disease profile and impacts, Article 5 on the eligibility of the
EFSA Panel on Animal Health and Welfare (AHAW) +27 more
doaj +2 more sources
APPLICATION OF MALDI-TOF MASS SPECTROMETRY AS A TOOL FOR BIOTYPING OF B. MELITENSIS [PDF]
Hamad Medical ...
Alsharabasi, Ola Asaad
core +4 more sources
Parenteral Vaccination with a Live Brucella melitensis Mutant Protects against Wild-Type B. melitensis 16M Challenge. [PDF]
Susceptibility to brucellosis remains prevalent, even in herds vaccinated with conventional vaccines. Efforts are underway to develop an improved brucellosis vaccine, and possibly a universal vaccine, given that Brucella species are highly homologous. To this end, two B.
Yang X +4 more
europepmc +4 more sources
Detection of Brucella melitensis and Brucella abortus strains using a single-stage PCR method
Brucella melitensis and Brucella abortus are of the most important causes of brucellosis, an infectious disease which is transmitted either directly or indirectly including consuming unpasteurized dairy products.
Alamian, S. +5 more
doaj +1 more source
Unravelling the challenge of cotrimoxazole and rifampin resistance in B. melitensis and B. abortus: A systematic review and meta-analysis. [PDF]
Background Brucellosis caused by Brucella (B. abortus) and Brucella melitensis (B. melitensis) poses a significant threat to human and animal populations. The World Health Organization (WHO) recommends rifampin and cotrimoxazole as first-line treatments for pediatric brucellosis.
Beig M +5 more
europepmc +4 more sources
Differentiation of Brucella abortus and B. melitensis biovars using PCR-RFLP and REP-PCR. [PDF]
Brucellosis is one of the most common zoonotic diseases of animal and human beings. This study aimed to differentiate the Brucella spp. and determines the patterns of biovars by using repetitive element palindromic (REP)-PCR and PCR restriction fragment length polymorphism (RFLP) methods.
Amoupour M +6 more
europepmc +4 more sources
Recovery of a medieval Brucella melitensis genome using shotgun metagenomics [PDF]
Shotgun metagenomics provides a powerful assumption-free approach to the recovery of pathogen genomes from contemporary and historical material. We sequenced the metagenome of a calcified nodule from the skeleton of a 14th-century middle-aged male ...
Milanese, Marco +25 more
core +3 more sources

