Results 101 to 110 of about 222,051 (168)

Involvement of Lamin B1 Reduction in Accelerated Cellular Senescence during Chronic Obstructive Pulmonary Disease Pathogenesis

Journal of Immunology, 2019
Downregulation of lamin B1 has been recognized as a crucial step for development of full senescence. Accelerated cellular senescence linked to mechanistic target of rapamycin kinase (MTOR) signaling and accumulation of mitochondrial damage has been ...
Nayuta Saito, J. Araya, Saburo Ito, K. Tsubouchi, S. Minagawa, Hiromichi Hara, A. Ito, Takayuki Nakano, Yusuke Hosaka, Akihiro Ichikawa, T. Kadota, Masahiro Yoshida, Y. Fujita, H. Utsumi, Yusuke Kurita, Kenji Kobayashi, Mitsuo Hashimoto, H. Wakui, T. Numata, Y. Kaneko, H. Asano, M. Odaka, T. Ohtsuka, T. Morikawa, K. Nakayama, K. Kuwano   +25 more
semanticscholar   +1 more source

UEG Week 2016 Poster Presentations

, 2016
United European Gastroenterology Journal, Volume 4, Issue S5, Page A157-A720, October 2016.
wiley   +1 more source

Cyclin B1 is essential for mitosis in mouse embryos, and its nuclear export sets the time for mitosis

Journal of Cell Biology, 2018
There is remarkable redundancy between the Cyclin–Cdk complexes that comprise the cell cycle machinery. None of the mammalian A-, D-, or E-type cyclins are required in development until implantation, and only Cdk1 is essential for early cell divisions ...
Bernhard Strauss, A. Harrison, P. A. Coelho, K. Yata, M. Zernicka-Goetz, J. Pines   +5 more
semanticscholar   +1 more source

Lamin B1 mapping reveals the existence of dynamic and functional euchromatin lamin B1 domains

Nature Communications, 2018
Lamins (A/C and B) are major constituents of the nuclear lamina (NL). Structurally conserved lamina-associated domains (LADs) are formed by genomic regions that contact the NL. Lamins are also found in the nucleoplasm, with a yet unknown function.
Laura Pascual-Reguant, E. Blanco, Silvia Galan, François le Dily, Yasmina Cuartero, Gemma Serra-Bardenys, V. Di Carlo, Ane Iturbide, Joan Pau Cebrià-Costa, L. Nonell, A. G. de Herreros, L. Di Croce, M. Martí-Renom, S. Peiró   +13 more
semanticscholar   +1 more source

Cyclin B2 can compensate for Cyclin B1 in oocyte meiosis I

Journal of Cell Biology, 2018
Mammalian oocytes are arrested at the prophase of the first meiotic division for months and even years, depending on species. Meiotic resumption of fully grown oocytes requires activation of M-phase–promoting factor (MPF), which is composed of Cyclin B1 ...
Jian Li, Ji‐Xin Tang, Jin‐Mei Cheng, Bian Hu, Yu-Qian Wang, Batool Aalia, Xiao-yu Li, Cheng Jin, Xiuxia Wang, S. Deng, Yan Zhang, Su-Ren Chen, Wei-Ping Qian, Qing-Yuan Sun, Xingxu Huang, Yi-Xun Liu   +15 more
semanticscholar   +1 more source

Sequence‐based mapping identifies a candidate transcription repressor underlying awn suppression at the B1 locus in wheat

New Phytologist, 2019
Summary Awns are stiff, hair‐like structures which grow from the lemmas of wheat (Triticum aestivum) and other grasses that contribute to photosynthesis and play a role in seed dispersal.
N. DeWitt, M. Guedira, Edwin Lauer, Martin Sarinelli, Priyanka Tyagi, D. Fu, Qunqun Hao, J. Murphy, D. Marshall, D. Marshall, Alina Akhunova, K. Jordan, E. Akhunov, G. Brown-Guedira, G. Brown-Guedira   +14 more
semanticscholar   +1 more source

Discovering Jewish Studies Collections in Academic Libraries: A Practical Guide

, 2014
The U.S. colleges and universities offering non-sectarian educational programs in Jewish Studies rely on the support of their academic libraries for research materials and library services.
Taler, Izabella
core  

B1 oligomerization regulates PML nuclear body biogenesis and leukemogenesis

Nature Communications, 2019
ProMyelocyticLeukemia (PML) protein can polymerize into a mega-Dalton nuclear assembly of 0.1–2 μm in diameter. The mechanism of PML nuclear body biogenesis remains elusive. Here, PMLRBCC is successfully purified.
Yuwen Li, Xiaodan Ma, Zhiming Chen, Haiyan Wu, Pengran Wang, Wenyu Wu, N. Cheng, L. Zeng, Hao Zhang, Xun Cai, Saijuan Chen, Zhu Chen, G. Meng   +12 more
semanticscholar   +1 more source

Structural basis of human separase regulation by securin and CDK1–cyclin B1

Nature, 2021
Jun Yu, P. Raia, C. M. Ghent, T. Raisch, Y. Sadian, S. Cavadini, Pramod M. Sabale, D. Barford, S. Raunser, D. Morgan, A. Boland   +10 more
semanticscholar   +1 more source

Lamin-B1 is a senescence-associated biomarker in clear-cell renal cell carcinoma

Oncology Letters, 2019
Clear-cell renal cell carcinoma (ccRCC) is a von-Hippel-Lindau gene (VHL) associated tumor disease. In addition to activating the hypoxia inducible factor (HIF) dependent oxygen-sensing pathway, VHL loss also has an impact on a HIF-independent senescence
Melissa Marie Radspieler, M. Schindeldecker, P. Stenzel, Sebastian Försch, K. Tagscherer, E. Herpel, M. Hohenfellner, G. Hatiboglu, W. Roth, S. Macher-Goeppinger   +9 more
semanticscholar   +1 more source