Results 51 to 60 of about 217,720 (158)

Naturalism and the task of philosophy

open access: yesFilosofický časopis, 2021
There is a plethora of naturalisms in contemporary philosophy. Instead of sorting out diverse past or present variants of this philosophical movement this article aims to define in three relatively simple points a version of naturalism that I consider as
Maco, Róbert
doaj   +1 more source

Blaming from Inside the Birdcage

open access: yesFeminist Philosophy Quarterly, 2022
This article notices a trend in work done by philosophers who build on P. F. Strawson’s account of the reactive attitudes; it looks as though philosophers supplement Strawson with (or claim that Strawson has underlying commitments to) a more robust ...
Amy McKiernan
doaj  

Quinean inspiration in feminist epistemology: on the potential alliance between naturalism and feminism

open access: yesFilosofický časopis, 2021
This article focuses on a critical analysis of some feminist epistemological initiatives that have been inspired by W. V. O. Quine’s project to naturalise epistemology.
Szapuová, Mariana
doaj   +1 more source

Lamin B1 decline underlies age‐related loss of adult hippocampal neurogenesis

open access: yesEMBO Journal, 2020
Neurogenesis in the adult hippocampus declines with age, a process that has been implicated in cognitive and emotional impairments. However, the mechanisms underlying this decline have remained elusive. Here, we show that the age‐dependent downregulation
T. Bedrosian   +12 more
semanticscholar   +1 more source

Aflatoxin B1 contamination in maize in Europe increases due to climate change

open access: yesScientific Reports, 2016
Climate change has been reported as a driver for emerging food and feed safety issues worldwide and its expected impact on the presence of mycotoxins in food and feed is of great concern.
P. Battilani   +8 more
semanticscholar   +1 more source

Molecular basis for the specific and multivariant recognitions of RNA substrates by human hnRNP A2/B1

open access: yesNature Communications, 2017
Human hnRNP A2/B1 is an RNA-binding protein that plays important roles in many biological processes, including maturation, transport, and metabolism of mRNA, and gene regulation of long noncoding RNAs.
Baixing Wu   +6 more
semanticscholar   +1 more source

HNRNPA2/B1 is upregulated in endocrine-resistant LCC9 breast cancer cells and alters the miRNA transcriptome when overexpressed in MCF-7 cells

open access: yesScientific Reports, 2019
MicroRNAs are dysregulated in breast cancer. Heterogeneous Nuclear Ribonucleoprotein A2/B1 (HNRNPA2/B1) is a reader of the N(6)-methyladenosine (m6A) mark in primary-miRNAs (pri-miRNAs) and promotes DROSHA processing to precursor-miRNAs (pre-miRNAs).
C. Klinge   +3 more
semanticscholar   +1 more source

An absence of lamin B1 in migrating neurons causes nuclear membrane ruptures and cell death

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2019
Significance Deficiencies in lamin B1 or lamin B2 in mice result in markedly reduced neuronal density in the cerebral cortex, but the mechanism has been unclear.
Natalie Y. Chen   +11 more
semanticscholar   +1 more source

Orchestration of the spindle assembly checkpoint by CDK1‐cyclin B1

open access: yesFEBS Letters, 2019
In mitosis, the spindle assembly checkpoint (SAC) monitors the formation of microtubule‐kinetochore attachments during capture of chromosomes by the mitotic spindle. Spindle assembly is complete once there are no longer any unattached kinetochores. Here,
D. Hayward   +2 more
semanticscholar   +1 more source

Lamin B1 loss promotes lung cancer development and metastasis by epigenetic derepression of RET

open access: yesJournal of Experimental Medicine, 2019
Jia et al. demonstrate that lamin B1 acts as a tumor suppressor in lung cancer. Lamin B1 loss promotes lung cancer development and metastasis by loss of PRC2 recruitment to chromatin and activation of the RET/p38 signaling axis.
Yanhan Jia   +15 more
semanticscholar   +1 more source

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