Results 211 to 220 of about 422,420 (292)

Multi‐Omics Integration Identifies a CDH3‐Associated Malignant Epithelial State and Immunosuppressive Niche to Predict Prognosis in Thymic Epithelial Tumors

Advanced Science, EarlyView.
Single‐cell, spatial, molecular, and pathology analyses identify a CDH3‐associated malignant epithelial state in thymic epithelial tumors. This state links stem‐like and EMT programs to M2 macrophage–rich immunosuppressive niches, genomic instability, poor survival, and drug vulnerability.
Yuntao Feng, Jingyu Chen, Lang Xia, Tao Wang, Yuzhou Wang, Lei Zhang, Guofang Zhao, Long Xu, Juemin Yu, Yunlang She, Junqi Wu, Yue Zhao, Chang Chen, Deping Zhao   +13 more
wiley   +1 more source

Effects of Solution Treatment on the Microstructure and Properties of Al_0.4Co_0.5V_0.2FeNi High-Entropy Alloys. [PDF]

Materials (Basel)
Duan H, Yang W, Ma Z, Li Y.
europepmc   +1 more source

Learning Work Function via Implicit Reasoning on Electrostatic Potential Landscapes

Advanced Science, EarlyView.
StructPot‐CLR establishes a cross‐modal contrastive learning framework that aligns the crystal structures of 2D materials with plane‐averaged electrostatic potential landscapes for physically informed work‐function prediction. The model achieves an MAE of 0.265 eV and an R2 of 0.902 on the held‐out test set while accurately preserving key morphological
Haoyu Wan, Yue Wu, Tianhao Su, Deng Pan
wiley   +1 more source

Incidence and predictors of surgical recurrence after primary ileocolic resection in Crohn ileitis: a systematic review and meta-analysis. [PDF]

Inflamm Bowel Dis
Haanappel AEG, van der Does de Willebois EML, Ali M, Jamaludin FS, Duijvestein M, Buskens CJ, Bemelman WA, de Groof EJ.   +7 more
europepmc   +1 more source

Vitamin B2

, 2016
Craig Hacking, Daniel Bell
openaire   +1 more source

Targeting β2‐Adrenergic Receptor Stability With Lycorine Reveals a Host‐Directed Pathway for Antiviral Defense Against Poxviruses

Advanced Science, EarlyView.
Chronic stress drives autophagy‐mediated β2‐AR degradation, impairing antiviral immunity and promoting poxvirus lethality. Lycorine directly stabilizes β2‐AR to restore host defense, suppress excessive inflammation and improve survival. ABSTRACT Psychological stress is a pervasive yet poorly understood modulator of infectious disease outcomes. Here, we
Xin Zhang, Shuqin Xu, Zixuan Zhang, Chenwen Wan, Xiaoqin Wang, Peihua Wang, Huini Yang, Tianxiao Huang, Yijia Yuan, Faiza Atique, Rui Yang, Yingli He, Zhijun Liu   +12 more
wiley   +1 more source

Dual-engineered extracellular vesicles enabling endothelial targeting and EphrinB2 delivery for pulp revascularization. [PDF]

J Nanobiotechnology
Liu A, Li M, Tang P, Ge W, Han Z, Dai Y, Zhang L, Yuan C, Qi L.   +8 more
europepmc   +1 more source

A Modular Variable Stiffness Co‐Bot System Achieving Tasks Flexibility and Contact Compliance

Advanced Science, EarlyView.
Bio‐inspired antagonistic compliance enables a modular rigid‐soft co‐bot platform with variable stiffness for safe human‐robot interaction (HRI): Standardized interfaces support application‐driven configurations with tailored DoFs, workspace, and stiffness range, making the system suited to HRI and low‐volume automation.
Wenlong Gaozhang, Yue Li, Jialei Shi, Yaxi Wang, Kaspar Althoefer, Agostino Stilli, Helge A. Wurdemann   +6 more
wiley   +1 more source

Neuronal Biomarkers and Micronutrient Status in Adults with Mild Cognitive Impairment. [PDF]

Nutrients
Vepakomma V, Geereddy B, Singireddy SS, Gurrala SR, Ramanujam K, Reddy GB.   +5 more
europepmc   +1 more source

AS‐TLC‐Based High‐Throughput Screening Integrated with CuAAC Optimization Strategy Facilitates the Rapid Discovery of YTHDC1 Inhibitor

Advanced Science, EarlyView.
We developed Affinity Selection Thin‐Layer Chromatography (AS‐TLC) as a method for high‐throughput screening (HTS) of compound mixtures. Furthermore, we integrated activity assays with AS‐TLC and identified a YTH domain‐containing protein 1 (YTHDC1) inhibitor. Building on this hit, we applied copper(I)‐catalyzed azide–alkyne cycloaddition (CuAAC) click
Mingchen Wang, Shuiping Fu, Ye Xu, Jia Gao, Jiwei Ren, Xu Yang, Hesong Xu, Ge Sun, Yanjie Li, Yanlin Wang, Lu Jin, Peijuan Chen, Ying Xu, Jianhao Li, Hua Lin, Chujiao Hu, Kaixian Chen, Huan Xiong, Cheng Luo, Shijie Chen   +19 more
wiley   +1 more source