Results 241 to 250 of about 422,420 (292)

TP53 Loss Elevates NF‐κB‐IFN‐β‐MHC‐Ia Signaling to Promote NK Cell Resistance in Osteosarcoma

Advanced Science, EarlyView.
TP53 loss in a transforming or osteosarcoma cell promotes cytosolic DNA accumulation, activating NF‐κB‐dependent IFN‐β production. Autocrine IFN‐β signaling increases cell‐surface HLA‐Ia expression, strengthens inhibitory KIR signaling in natural killer cells, and thereby enables the affected cell to evade NK cell‐mediated cytotoxicity.
Guihui Qin, Cheung Kwan Yeung, Ye Yi, Dejin Zheng, Miaoman Ye, Chi‐Chong Chio, Jinjie Wu, Siyi Fu, Chu‐Xia Deng, Ren‐He Xu   +9 more
wiley   +1 more source

ZrCo₃B₂ and HfCo₃B₂ Electrodes Go on Stage for Oxygen Evolution Reaction. [PDF]

Adv Sci (Weinh)
Aras F, Burkhardt U, Altendorf SG, Grin Y, Antonyshyn I.   +4 more
europepmc   +1 more source

Structural Basis of Lymphangiogenic Receptor VEGFR‐3 Activation Mediated by Distinctive Clustering of the Ligand–Receptor Complex

Advanced Science, EarlyView.
VEGF‐C and its receptor VEGFR‐3 are critical for lymphangiogenesis. Cryo‐EM structures of the VEGFR‐3/VEGF‐C ectodomain complex reveal a canonical 2:2 ligand–receptor hetero‐tetramer that further assembles into higher‐order clusters beyond simple receptor dimerization.
Ryeongeun Cho, Jinsook Ahn, Jimin Yang, Dong Sun Lee, Gahi Hong, Sangkyu Lee, Ho Min Kim   +6 more
wiley   +1 more source

MR-CISD investigation (including extensivity corrections) of Rydberg n-3 s and n-3p states of the smallest ionized HCl-water cluster. [PDF]

J Mol Model
Bezerra MG, Ventura E, do Monte SA.
europepmc   +1 more source

A 3D‐Printed SFE‐Graded Alloy Mitigates Cryogenic Discontinuous Plastic Flow and Hydrogen Embrittlement

Advanced Science, EarlyView.
A novel strategy features gradient composition and stacking fault energy‐tuned (CoCrMn)100‐2xFexNix fabricated via in situ alloying additive manufacturing. This design circumvents cryogenic discontinuous plastic flow and hydrogen embrittlement of metallic materials under quasi‐static loading and hydrogen‐rich environment relevant to lunar polar ...
Renhao Wu, Ao Geng, Peihao Geng, Hyojin Park, Eun Seong Kim, Sang‐Ho Oh, Stephan Schönecker, Xiaoqing Li, Tianlong Zhang, Shuhui Li, Byeong‐Joo Lee, Hyoung Seop Kim   +11 more
wiley   +1 more source

Synergistic remediation of oil-contaminated soil using sorghum and oil sludge-derived biochar. [PDF]

Sci Rep
Mohammadzadeh Shirazi H, Pourbabaee AA, Etesami H, Asadi H.   +3 more
europepmc   +1 more source

Optimization of Ultrasonic Parameters and Model Development for Nondestructive CTE Measurement of LAS Ultra-Low-Expansion Glass Ceramics. [PDF]

Materials (Basel)
Chang S, Wei W, Qi X, Wang X, Zhang Z, Gu J, Mo D, Deng H.   +7 more
europepmc   +1 more source

Vehicle-Mounted Vision Sensing for Large-Scale Road Surface Monitoring: A Multi-Year Field Study of Acquisition Geometry and a Heterogeneous Detection-Classification Pipeline for Pothole Mapping. [PDF]

Sensors (Basel)
Lee MS, Han SY.
europepmc   +1 more source

Delayed maturation of the milk microbiome in women with type 1 diabetes. [PDF]

Diabetologia
Roth-Schulze AJ, Ngui KM, Martin G, Ashwood P, Thomson RL, Zozaya-Valdes E, Gao Y, Wentworth JM, Craig ME, Huynh A, Couper JJ, Penno MAS, Harrison LC, ENDIA Study Group.   +13 more
europepmc   +1 more source

Leveraging CNN and Transfer Learning With EfficientNet for Enhanced Optical Coherence Tomography (OCT). [PDF]

Int J Biomed Imaging
Arekanti S, Bhushan CM, Alam I, Koppuravuri P, Shaik F, Hussain MM, Gazi F.   +6 more
europepmc   +1 more source