Purification and partial characterization of outer membrane proteins P5 and P6 from Haemophilus influenzae type b [PDF]
The major outer membrane proteins of Haemophilus influenzae type b (Hib), designated P5 and P6 (R.S. Munson, Jr., J.L. Shenep, S.J. Barenkamp, and D.M. Granoff, J. Clin. Invest. 72:677-684, 1983), were purified to homogeneity and partially characterized. P5 was insoluble in octylglucoside-NaCl and could be extracted with 1% sodium dodecyl sulfate (SDS)
R S, Munson, D M, Granoff
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Evaluation of C-terminal p7 (NC)-p6 Gag genetic variants among HIV-1 non-B subtypes in a subset of Cameroonian patients [PDF]
Abstract Response to ritonavir-boosted-protease inhibitors (PI/r)-based regimen is associated with some Gag mutations among HIV-1 B-clade. There is limited data on Gag variants and their covariation with mutations in protease among HIV-1 non-B-clades at PI/r-based treatment failure.
Georges Teto +15 more
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15P Change of mTOR, p6, NBR1 and LC3A/B-I/II in A549 cells treated with graphene oxides [PDF]
Background: Measuring levels of ligands in peripheral blood representing systemic circulation and in blood isolated from tumour vascular bed accompanied by evaluation of binding receptor expression in tumour tissue gives insight into cancerogenesis.
Shin, J.W. +8 more
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Persistent replication of a hepatitis C virus genotype 1b‐based chimeric clone carrying E1, E2 and p6 regions from GB virus B in a New World monkey [PDF]
ABSTRACTThe development of effective hepatitis C virus (HCV) vaccines is essential for the prevention of further HCV dissemination, especially in developing countries. Therefore the aim of this study is to establish a feasible and immunocompetent surrogate animal model of HCV infection that will help in evaluation of the protective efficacy of newly ...
Saori, Suzuki +6 more
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Serum Concentrations of Antibodies against Outer Membrane Protein P6, Protein D, and T- and B-Cell Combined Antigenic Epitopes of Nontypeable Haemophilus influenzae in Children and Adults of Different Ages [PDF]
ABSTRACT Nontypeable Haemophilus influenzae (NTHi) is one of the most common etiologies of acute otitis media, rhinosinusitis, and pneumonia. Outer membrane proteins (OMPs) are the main focus in new vaccine development against NTHi, as the H. influenzae type b (Hib) vaccine does not
Chun-Zhen, Hua +5 more
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A recombinant non-fatty acylated form of the Hi-PAL (P6) protein of Haemophilus influenzae elicits biologically active antibody against both nontypeable and type b H. influenzae [PDF]
An approximately 15,000-dalton outer membrane lipoprotein of Haemophilus influenzae, the Hi-PAL (P6) protein, has been shown to elicit bactericidal and protective antibodies against both type b and nontypeable H. influenzae strains and is a vaccine candidate for these organisms.
B A, Green +5 more
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This note operationalizes P6 by replacing abstract error terms with executable proxies suitable for third-party audit. P6-B1 defines discretization/inner-product consistency checks (energy and cross-grid drift). P6-B2 defines a resolution-convergence proxy for the whitened antisymmetry operator via a two-grid difference diagnostic.
Jian Lin
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The photocatalytic degradation of wastewater containing three industrial dyes belonging to different families, methyl orange (MO), methylene blue (MB) and Rhodamine B (RhB), was studied under UV-Vis irradiation using synthesised silver chloride nanoparticles.
Borja, Rodríguez-Cabo +6 more
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Generation of a Bioengineered Substitute of the Human Sclero-Corneal Limbus Using a Novel Decellularization Method [PDF]
Background: Severe dysfunction of the human limbus associated with limbal stem cell deficiency is a therapeutic challenge, especially when a structural alteration of the limbal niche is associated.
Paula Ávila-Fernández +7 more
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Identification of dominant peptide epitopes and antibody response to the spike protein of SARS-CoV-2 [PDF]
ObjectiveMultiple antigenic epitopes are present in the spike (S) protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), but they exhibit significant variation in immunogenicity and reactogenicity. We aimed to investigate the reactivity
Xianyan Zhang +7 more
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