Results 11 to 20 of about 1,648 (133)

Taming interleukin-12: Engineering of bispecific antibody-based IL-12 mimetics with biased agonism capacities. [PDF]

open access: yesProtein Sci
Abstract In this work, we have generated bispecific interleukin (IL)‐12 surrogate agonists based on camelid‐derived single‐domain antibodies (sdAbs) targeting the IL‐12 receptor (IL‐12R) subunits IL‐12Rβ1 and IL‐12Rβ2. Following immunization and antibody display‐based paratope isolation, respective sdAbs were combinatorially reformatted into a ...
Lipinski B   +19 more
europepmc   +2 more sources

Effectiveness of Natural Frequency Technology® on cognition, sleep, and mood of adults with high perceived stress: A randomized, double-blind, placebo-controlled crossover study. [PDF]

open access: yesBrain Behav, 2020
NexQuest Natural Frequency Technology® (NFT), intended to enhance biological function using naturally occurring frequencies, may be a nonpharmacological intervention to improve stress and overall health. Using a randomized placebo‐controlled design, we found that the NFT resulted in significant improvements in sleep quality, perceived stress, cognition
Hausenblas HA   +3 more
europepmc   +2 more sources

Headline Impression Management in the Earnings Press Releases of TSX Venture Exchange Firms*

open access: yesAccounting Perspectives, Volume 22, Issue 4, Page 519-556, December 2023., 2023
ABSTRACT This paper explores firms traded on the Toronto Stock Exchange (TSX) Venture Exchange and their voluntary disclosure practices by focusing on earnings press releases (EPRs). We compare the characteristics of EPR issuers and non‐issuers and investigate how the former group uses headline impression management in their EPRs to highlight firm ...
Alisher Mansurov   +2 more
wiley   +1 more source

Northern and Southern Hemisphere Polar Cap Indices: To What Extent Do They Agree and to What Extent Should They Agree?

open access: yesJournal of Geophysical Research: Space Physics, Volume 128, Issue 7, July 2023., 2023
Abstract The IAGA‐endorsed Polar Cap Indices for the northern and southern hemispheres, PCN and PCS, are compared for 1998–2018, inclusive. Potential effects of the slightly different, and changing, magnetic coordinates of the two magnetic stations employed, Thule (Qaanaaq) in Greenland and Vostok in Antarctica, are investigated.
M. Lockwood
wiley   +1 more source

Application of New Energy Composites in Sports Facilities and Fitness Equipment

open access: yesJournal of Nanomaterials, Volume 2022, Issue 1, 2022., 2022
New energy composite is an advanced material that can replace the traditional single metal material, especially the newly developed or developed material with superior performance. At present, the material is widely used in automobile manufacturing and other fields, but there is a lack of development and application of the material in the field of ...
Jiejian Zhang, Yang Mi, Awais Ahmed
wiley   +1 more source

Nanocrystalline hydroxyapatite/si coating by mechanical alloying technique. [PDF]

open access: yesBioinorg Chem Appl, 2012
A novel approach for depositing hydroxyapatite (HA) films on titanium substrates by using mechanical alloying (MA) technique has been developed. However, it was shown that one‐hour heat treatment at 800°C of such mechanically coated HA layer leads to partial transformation of desired HA phase to beta‐tri‐calcium phosphate (β‐TCP) phase. It appears that
Hannora AE, Mukasyan AS, Mansurov ZA.
europepmc   +2 more sources

Acoustic Emission Experimental Research of the Damage Characteristics of Raw Coal under Different Loading and Unloading Rates

open access: yesShock and Vibration, Volume 2020, Issue 1, 2020., 2020
In this study, triaxial load failure experiments of coal samples under different strain rates and different confining pressure unloading rates were carried out using an RTX‐1000 rock triaxial apparatus, and the acoustic emission characteristic parameters of a Micro‐II acoustic emission imaging acquisition instrument were used to study the acoustic ...
Minbo Zhang   +6 more
wiley   +1 more source

Plasma flows, Birkeland currents and auroral forms in relation to the Svalgaard-Mansurov effect [PDF]

open access: yes, 2012
The traditional explanation of the polar cap magnetic deflections, referred to as the Svalgaard-Mansurov effect, is in terms of currents associated with ionospheric flow resulting from the release of magnetic tension on newly open magnetic field ...
C. J. Farrugia, P. E. Sandholt
core   +2 more sources

Energy Evolution and Acoustic Emission Characteristics of Sandstone Specimens under Unloading Confining Pressure

open access: yesShock and Vibration, Volume 2019, Issue 1, 2019., 2019
The acoustic emission characteristics of rock specimens under different initial unloading confining pressures were tested to obtain the damage and rupture characteristics of the sandstone unloading confining pressure path. The CT scan and three‐dimensional reconstruction of the fractured rock specimens were carried out to study the differences of ...
Tao Qin   +5 more
wiley   +1 more source

Solidification dynamics under random external-temperature fluctuations [PDF]

open access: yes, 2013
The nonlinear dynamic mechanisms of solid-phase formation with a phase transition region are studied under periodic and random fluctuations of the cooling-boundary temperature. It is theoretically shown that a mushy zone can form even at close liquid and
Alexandrov, D. V.   +3 more
core   +1 more source

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