Comparative efficacy of buparvaquone and imidocarb in inhibiting the in vitro growth of Babesia bovis. [PDF]
Front PharmacolIntroduction: B. bovis is an apicomplexan parasite responsible for bovine babesiosis, a tick-borne disease with a worldwide impact. The disease remains inefficiently controlled, and few effective drugs, including imidocarb dipropionate (ID), are ...
Cardillo NM +8 more
europepmc +2 more sources
Identification of CCp5 and FNPA as Novel Non-canonical Members of the CCp Protein Family in Babesia bovis. [PDF]
Front Vet Sci, 2022 Bovine babesiosis, caused by Babesia bovis, is an economically significant tick-borne disease that imposes restrictions to livestock production worldwide.
Ozubek S +4 more
europepmc +2 more sources
Unraveling the Complexity of the Rhomboid Serine Protease 4 Family of Babesia bovis Using Bioinformatics and Experimental Studies. [PDF]
Pathogens, 2022 Babesia bovis, a tick-transmitted apicomplexan protozoon, infects cattle in tropical and subtropical regions around the world. In the apicomplexans Toxoplasma gondii and Plasmodium falciparum, rhomboid serine protease 4 (ROM4) fulfills an essential role ...
Gallenti R +11 more
europepmc +2 more sources
A Culture-Adapted Strain of Babesia bovis Has Reduced Subpopulation Complexity and Is Unable to Complete Its Natural Life Cycle in Ticks. [PDF]
Front Cell Infect Microbiol, 2022 Babesia bovis natural field strains are composed of several geno-phenotypically distinct subpopulations. This feature, together with possible epigenetic modifications, may facilitate adaptation to variable environmental conditions.
Alzan HF +6 more
europepmc +2 more sources
Isolation of viable Babesia bovis merozoites to study parasite invasion. [PDF]
Sci Rep, 2021 Babesia parasite invades exclusively red blood cell (RBC) in mammalian host and induces alterations to host cell for survival. Despite the importance of Babesia in livestock industry and emerging cases in humans, their basic biology is hampered by lack ...
Hakimi H, Asada M, Ishizaki T, Kawazu S.
europepmc +2 more sources
Parasites & Vectors, 2021 Background Babesia bovis is one of the most significant tick-transmitted pathogens of cattle worldwide. Babesia bovis parasites have a complex lifecycle, including development within the mammalian host and tick vector.
Hala E. Hussein +6 more
doaj +2 more sources
Comparative Study of Indirect Fluorescent Antibody, ELISA, and Immunochromatography Tests for Serological Diagnosis of Bovine Babesiosis Caused by Babesia bovis. [PDF]
Animals (Basel), 2021 Simple Summary Currently serological diagnosis of bovine babesiosis is based on the detection of Babesia-specific antibodies (immunoglobulin-G). Antibody detection is commonly used in seroepidemiological studies or in the assessment of antibabesial ...
Lira-Amaya JJ +6 more
europepmc +2 more sources
Establishment of Babesia bovis In Vitro Culture Using Medium Free of Animal Products. [PDF]
Pathogens, 2021 Babesia bovis, an etiological agent of bovine babesiosis, causes a significant burden to the cattle industry worldwide. The most efficient method to mitigate bovine babesiosis is a live vaccine produced by serial passage in splenectomized cattle. However,
Álvarez Martínez JA +3 more
europepmc +2 more sources
Assessment of Babesia bovis 6cys A and 6cys B as components of transmission blocking vaccines for babesiosis. [PDF]
Parasit Vectors, 2021 Background Babesia bovis reproduces sexually in the gut of its tick vector Rhipicephalus microplus , which involves expression of 6cys A and 6cys B proteins.
Alzan HF +6 more
europepmc +2 more sources
Gapless assembly of Babesia bovis NVSL348. [PDF]
Microbiol Resour AnnouncABSTRACT We are reporting a Babesia bovis genome containing four nuclear chromosomes, a mitochondrial genome, and an apicoplast from reference isolate NVSL348. This report includes a gapless assembly consisting of all six genetic molecules.
Grimsley M +4 more
europepmc +3 more sources