Results 11 to 20 of about 112 (84)

Controlling Enzymatic Activity by Modulating the Oligomerization State via Chemical Rescue and Optical Control. [PDF]

open access: yesChembiochem, 2022
Exogenous control of the association state of enzyme complexes can be used to switch activity. A cation‐π bond in the oligomerization interface was disrupted either by a Lys‐to‐Cys mutation or by incorporation of an unnatural amino acid (UAA), resulting in complex disassembly and loss of activity.
Kropp C, Bruckmann A, Babinger P.
europepmc   +2 more sources

Hexamerization and thermostability emerged very early during geranylgeranylglyceryl phosphate synthase evolution. [PDF]

open access: yesProtein Sci, 2021
Abstract A large number of archaea live in hyperthermophilic environments. In consequence, their proteins need to adopt to these harsh conditions, including the enzymes that catalyze the synthesis of their membrane ether lipids. The enzyme that catalyzes the formation of the first ether bond in these lipids, geranylgeranylglyceryl phosphate synthase ...
Kropp C, Straub K, Linde M, Babinger P.
europepmc   +2 more sources

Sequence and functional differences in the ATPase domains of CHD3 and SNF2H promise potential for selective regulability and drugability

open access: yesThe FEBS Journal, Volume 288, Issue 13, Page 4000-4023, July 2021., 2021
The chromatin remodelers CHD3 and SNF2H are central regulators of chromatin structure by repositioning histone octamers on DNA in an ATP‐dependent mechanism. Sequence differences in the ATPase domain make CHD3 a more energy efficient chromatin remodeling enzyme and being less susceptible to competitive inhibition by ADP.
Helen Hoffmeister   +9 more
wiley   +1 more source

Biocatalytic Ether Lipid Synthesis by an Archaeal Glycerolprenylase

open access: yesAngewandte Chemie, Volume 136, Issue 46, November 11, 2024.
The ultrastable geranylgeranylglyceryl phosphate synthase from Archaeoglobus fulgidus makes various (E)‐ and (Z)‐configured prenyl glycerol ethers from the corresponding pyrophosphates while exerting perfect control over the configuration at the glycerol unit.
Felix Kaspar   +10 more
wiley   +2 more sources

El turismo ante el reto de peligros naturales recurrentes: una visión desde Cancún

open access: yesInvestigaciones Geográficas, 2012
Este artículo analiza la dualidad existente entre el desarrollo económico basado en la actividad turística y las repercusiones de su ocupación territorial a expensas de un medio ambiente que engloba unos peligros naturales determinados. La transformación
Frank Babinger
doaj  

Sjećanja

open access: yesAnali Gazi Husrev-Begove Biblioteke, 1972
U posljednjih nekoliko godina umro je veći broj naučenjaka - naših i stranih - koji su se na ovaj ili onaj način bavili kultur­nom baštinom bosanskih Muslima­na.
Muhamed Hadžijahić
doaj  

Investigating the Prevalence of RNA-Binding Metabolic Enzymes in E. coli. [PDF]

open access: yesInt J Mol Sci, 2023
Klein T   +8 more
europepmc   +1 more source

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