Results 31 to 40 of about 4,758 (125)
Molecular dynamics of the host response to Streptococcus pneumoniae pneumonia in baboons
Using an established, clinically relevant nonhuman primate model of S. pneumoniae pneumonia, this study aims to identify novel potential molecular diagnostic and therapeutic targets using peripheral blood bulk transcriptomic, unbiased proteomic, and cytokine measurements. The constructed models were highly accurate in classifying bacterial pneumonia in
Bryan D. Kraft +18 more
wiley +1 more source
Artificial intelligence in preclinical epilepsy research: Current state, potential, and challenges
Abstract Preclinical translational epilepsy research uses animal models to better understand the mechanisms underlying epilepsy and its comorbidities, as well as to analyze and develop potential treatments that may mitigate this neurological disorder and its associated conditions. Artificial intelligence (AI) has emerged as a transformative tool across
Jesús Servando Medel‐Matus +7 more
wiley +1 more source
Cardiovascular Plasticity and Adaptation of High‐Altitude Birds and Mammals
This schematic depicts the cardiovascular adaptations of mammals and birds to high‐altitude hypoxia. It highlights key phenotypic changes in oxygen transport and cardiac responses, driven by molecular mechanisms including transcriptional regulation and genetic modifications.
Huishang She, Yanhua Qu
wiley +1 more source
Background Baboons (Papio hamadryas Sp.) develop features of the cardiometabolic syndrome and represent a clinically-relevant animal model in which to study the aetiology of the disorder.
Tejero M Elizabeth +11 more
doaj +1 more source
Modeling cerebral palsy in animals
Abstract Advancements in the treatment of cerebral palsy depend on animal research. Yet, most animal models have not been fully evaluated for spasticity and dystonia using clinically relevant measures of altered tone or movement patterns, which form the basis for diagnosing people with the condition.
Katharina A. Quinlan +8 more
wiley +1 more source
Baboon syndrome and segmental vitiligo coexistence
The baboon syndrome is a form of systemic contact dermatitis with skin eruptions in the area of the buttocks and major flexures. Inhalation of mercury vapor causes this rare but distinctive eruption.
Serap Utaş, Ayten Ferahbaş
doaj
ABSTRACT We study the effect of royal status—a historically rooted legal privilege enjoyed by hereditary monarchs and their families—on human longevity, a proxy of individuals' health capital. We disentangle the effect of royal status that encompassed serving as heads of state, and hence being subject to status, from that of other family members and ...
Alberto Batinti +2 more
wiley +1 more source
Acquired Localized Hypertrichosis Induced by Rivastigmine
Hypertrichosis is the excessive hair growth in any area of the skin surface. Acquired localized hypertrichosis may be secondary to multiple causes and there is a secondary form due to several drugs, which is usually reversible with discontinuation of the
Adrian Imbernón-Moya +6 more
doaj +1 more source
Genomic Signatures of Island Colonisation in Highly Diverse Primates
ABSTRACT Understanding how small populations cope with loss of genetic diversity and deleterious variation is crucial to address the current biodiversity crisis. Insular populations are particularly interesting as they have often persisted at lower population sizes and higher inbreeding than their mainland counterparts.
I. Colmonero‐Costeira +12 more
wiley +1 more source
Baboon syndrome induced by oral antitussive-decongestant agent in a child
We present the case of a three-year-old boy who developed a special exanthem after oral intake of an antitussive-decongestant agent. The clinical findings were compatible with baboon syndrome.
Halil Ozdemir +6 more
doaj

